Evidence map›Paper›PMID 30526279›Full record

ArticleHuman vaccines & immunotherapeutics2019

Cost calculator for mass vaccination response to a US college campus outbreak of serogroup B meningococcal disease.

Elizabeth M La, Sandra E Talbird, Koren V Kanadanian, Liping Huang, Joel Fain, Amit Srivastava

Abstract read
In one paragraph

Article in Human vaccines & immunotherapeutics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Evolution of invasive meningococcal disease epidemiology in Europe, 2008 to 2017.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2022
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Elizabeth M Laa RTI Health Solutions , Research Triangle Park , NC , USA.ORCID 0000-0001-5652-8961
Sandra E Talbirda RTI Health Solutions , Research Triangle Park , NC , USA.ORCID 0000-0003-4719-3703
Koren V Kanadanianb Emergency Management , Providence College , Providence , RI , USA.
Liping Huangc Outcomes and Evidence, Pfizer Inc , Collegeville , PA , USA.
Joel Faind US Medical Affairs, Pfizer Inc , Collegeville , PA , USA.
Amit Srivastavae US Medical Affairs, Pfizer Inc , Cambridge , MA , USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Serogroup B (MenB) is the leading cause of meningococcal disease among 16- to 23-year-olds in the United States and has been responsible for all 10 college outbreaks between 2011 and 2017. Outbreak-associated costs levy a substantial and unforeseen burden on colleges/universities and surrounding communities, in part because they involve collaboration with local and state health departments to develop points-of-dispensing (PODs) outbreak response plans and rapid mass vaccination of a large at-risk student population. The MenB outbreak at Providence College in 2015 was used as a case study to develop an Excel-based Meningococcal Outbreak Cost Calculator that uses target populations for mass vaccination to estimate the costs and resources associated with a meningococcal disease outbreak response. Resources include labor, medical supply, and other nonlabor costs (eg, vaccine-related adverse event costs) over an 18-month period following the outbreak declaration. Based on the actual Providence College population partially or fully vaccinated with MenB-FHbp (Trumenba®, Bivalent rLP2086) (3-dose schedule), the calculator estimated aggregate direct costs of $1,350,963 over 18 months post-outbreak for 4,418 individuals. For planned full vaccination of the enrolled undergraduate population (4,795 individuals), the tool estimated total costs of $1,798,399. In both cases, the majority of costs were for medical supplies (88%-89%) and contract services (7%-9%). This calculator can help to plan a mass vaccination campaign for MenB outbreak control, and underscores the need to vaccinate pre-emptively against diverse disease-causing strains before an outbreak occurs.

Indexed as

AdolescentDisease OutbreaksHumansMass VaccinationMeningitis, MeningococcalMeningococcal InfectionsMeningococcal VaccinesNeisseria meningitidis, Serogroup BSerogroupStudentsUnited StatesUniversitiesYoung AdultMeningococcal VaccinesCollegecostsIMDMenB-FHBpoutbreakserogroup B meningococcal diseasevaccine

Identifiers

PMID30526279
PMCPMC6605861

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.