Evidence map›Paper›PMID 30526183›Full record

Trial reportActa orthopaedica2019

Similar polyethylene wear between cemented and cementless Oxford medial UKA: a 5-year follow-up randomized controlled trial on 79 patients using radiostereometry.

Kristian Horsager, Frank Madsen, Anders Odgaard, Claus Fink Jepsen, Lone Rømer, Per Wagner Kristensen, Bart L Kaptein, Kjeld Søballe, Maiken Stilling

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Acta orthopaedica, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Review
  6. Review
  7. Review
  8. Low polyethylene creep and wear following mobile-bearing unicompartmental knee replacement.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2021
    Article
  9. Article
  10. [Research progress in unicompartmental knee arthroplasty].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kristian Horsagera Department of Clinical Institute , Aarhus University , Aarhus , Denmark.
Frank Madsenb Department of Orthopedics , Aarhus University Hospital , Aarhus , Denmark.
Anders Odgaardc Department of Orthopaedics , Herlev-Gentofte Hospital, Copenhagen University Hospital , Hellerup , Denmark.
Claus Fink Jepsenb Department of Orthopedics , Aarhus University Hospital , Aarhus , Denmark.
Lone Rømerd Department of Radiology , Aarhus University Hospital , Aarhus , Denmark.
Per Wagner Kristensene Department of Orthopedics , Vejle Hospital , Vejle , Denmark.
Bart L Kapteinf Department of Orthopedic Surgery, Biomechanics and Imaging Group , Leiden University Medical Center , Leiden , Netherlands.
Kjeld Søballea Department of Clinical Institute , Aarhus University , Aarhus , Denmark.
Maiken Stillinga Department of Clinical Institute , Aarhus University , Aarhus , Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and purpose - Hydroxyapatite (HA)-coated implants have been associated with high polyethylene wear in hip arthroplasties. HA coating as a promoter of wear in knee arthroplasties has not been investigated. We compared the wear-rate of the polyethylene bearing for cemented and cementless HA-coated Oxford medial unicondylar knee arthroplasties (UKA). Secondarily, we investigated whether wear-rates were influenced by overhang or impingement of the bearing. Patients and methods - 80 patients (mean age 64 years), treatment-blinded, were randomized to 1 of 3 Oxford medial UKA versions: cemented with double-pegged or single-pegged femoral component or cementless HA-coated with double-pegged femoral component (ratios 1:1:1). We compared wear between the cemented (n = 55) and cementless group (n = 25) (ratio 2:1). Wear, impingement, and overhang were quantified between surgery and 5-year follow-up using radiostereometry. Clinical outcome was evaluated with the Oxford Knee Score. Results - The mean wear-rate for patients without bearing overhang was 0.04 mm/year (95% CI 0.02-0.07) for the cemented group and 0.05 mm/year (CI 0.02-0.08) for the cementless group. The mean difference in wear was 0.008 mm/year (CI -0.04 to 0.03). No impingement was identified. Half of the patients had medial bearing overhang, mean 2.5 mm (1-5). Wear increased by 0.014 mm/year for each mm increment in overhang. The mean Oxford Knee Score was 39 for the cementless group and 38 for the cemented group at the 5-year follow-up. Interpretation - The wear-rates were similar for the 2 fixation methods, which supports further use of the cementless Oxford medial UKA. However, a caveat is a relatively large 95% CI of the mean difference in wear-rate. Component size and position is important as half of the patients presented with an additional increase in wear-rate due to medial bearing overhang.

Indexed as

Arthroplasty, Replacement, KneeBone CementsCementationCoated Materials, BiocompatibleFemaleFollow-Up StudiesHumansKnee ProsthesisMaleMiddle AgedOsteoarthritis, KneePolyethyleneProsthesis DesignProsthesis FailureRadiostereometric AnalysisTreatment OutcomeBone CementsCoated Materials, BiocompatiblePolyethylene

Identifiers

PMID30526183
PMCPMC6366473

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.