Evidence map›Paper›PMID 30525876›Full record

ArticleAmerican journal of Alzheimer's disease and other dementias2019

Feasibility and Impact of a Multicomponent Exercise Intervention in Patients With Alzheimer's Disease: A Pilot Study.

Flávia Borges-Machado, Óscar Ribeiro, Arnaldina Sampaio, Inês Marques-Aleixo, Joana Meireles, Joana Carvalho

Abstract readClinical Study
In one paragraph

Article in American journal of Alzheimer's disease and other dementias, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Flávia Borges-Machado1 CIAFEL-Research Centre in Physical Activity, Health and Leisure, Porto, Portugal.ORCID 0000-0002-8839-5726
Óscar Ribeiro3 CINTESIS-Center for Health Technology and Services Research, Porto, Portugal.
Arnaldina Sampaio1 CIAFEL-Research Centre in Physical Activity, Health and Leisure, Porto, Portugal.
Inês Marques-Aleixo1 CIAFEL-Research Centre in Physical Activity, Health and Leisure, Porto, Portugal.
Joana Meireles6 Faculty of Medicine, University of Porto, Porto, Portugal.
Joana Carvalho1 CIAFEL-Research Centre in Physical Activity, Health and Leisure, Porto, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This quasi-experimental, nonrandomized study examined the feasibility and impact of a multicomponent (MT) intervention on 7 community-dwelling individuals diagnosed with probable Alzheimer's disease (AD) at mild to moderate stage. During 6 months, patients with AD and their caregivers were submitted to a biweekly exercise program, including muscle strengthening, aerobics, balance, and postural exercises. The following tests were used: Senior Fitness Test and Incremental Treadmill Test, Disability Assessment for Dementia Scale, Alzheimer Disease Assessment Scale-Cognitive, and Quality of Life-Alzheimer's. Attendance and retention mean rates were high (86% and 78%, respectively). No adverse events occurred. Results revealed a significant beneficial effect on cardiorespiratory fitness ( P = .028), upper ( P = .018) and lower ( P = .026) body muscle strength, agility ( P = .018), and ability to perform daily activities ( P = .018). Data suggest that a biweekly MT intervention is feasible to conduct in patients with AD. Findings also suggest a potential positive effect on mitigating cognitive decline and in positively influencing quality of life.

Indexed as

Activities of Daily LivingOutcome and Process Assessment, Health CareAgedAged, 80 and overAlzheimer DiseaseCardiorespiratory FitnessCaregiversExercise TherapyFeasibility StudiesFemaleHumansMaleMiddle AgedMuscle Strengthdementiafunctionalitymultimodal interventionneurocognitive disorderphysical activityquality of life

Identifiers

PMID30525876
PMCPMC10852450

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.