Evidence map›Paper›PMID 30525501›Full record

ArticleEnvironmental science & technology2019

Identification of Steps in the Pathway of Arsenosugar Biosynthesis.

Xi-Mei Xue, Jun Ye, Georg Raber, Barry P Rosen, Kevin Francesconi, Chan Xiong, Zhe Zhu, Christopher Rensing, Yong-Guan Zhu

Abstract read
In one paragraph

Article in Environmental science & technology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 40 citations in OpenAlex.

  1. Synergistic function of ars genes in arsenic detoxification and biosynthesis of organoarsenicals.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026
    Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Antimicrobial Activity of Metals and Metalloids.Annual review of microbiology · 2021
    Review
  7. Article
  8. Article
  9. Bioaccumulation and biotransformation of arsenic in Leptolyngbya boryana.Environmental science and pollution research international · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Xi-Mei XueKey Laboratory of Urban Environment and Health, Institute of Urban Environment , Chinese Academy of Sciences , Xiamen 361021 , China.
Jun YeKey Laboratory of Urban Environment and Health, Institute of Urban Environment , Chinese Academy of Sciences , Xiamen 361021 , China.
Georg RaberInstitute of Chemistry, NAWI Graz , University of Graz , Graz 8010 , Austria.ORCID 0000-0002-7674-5995
Barry P RosenDepartment of Cellular Biology and Pharmacology, Herbert Wertheim College of Medicine , Florida International University , Miami , Florida 33199 , United States.ORCID 0000-0002-5230-4271
Kevin FrancesconiInstitute of Chemistry, NAWI Graz , University of Graz , Graz 8010 , Austria.ORCID 0000-0002-2536-0542
Chan XiongInstitute of Chemistry, NAWI Graz , University of Graz , Graz 8010 , Austria.ORCID 0000-0002-9975-945X
Zhe ZhuDepartment of Chemical and Environmental Engineering, Faculty of Science and Engineering , University of Nottingham , Ningbo 315100 , China.
Christopher RensingCollege of Resources and Environment , Fujian Agriculture and Forestry University , Fuzhou 350002 , China.
Yong-Guan ZhuKey Laboratory of Urban Environment and Health, Institute of Urban Environment , Chinese Academy of Sciences , Xiamen 361021 , China.ORCID 0000-0003-3861-8482
Chinese Academy of Sciences · CNUniversity of Graz · ATFlorida International University · USFujian Agriculture and Forestry University · CNUniversity of Nottingham Ningbo China · CN

Funding

Mechanisms of Arsenic Transport and BiotransformationsR01GM055425 · NIGMS · WAYNE STATE UNIVERSITY · PI ROSEN, BARRY P. · 1997 to 2019
$3.8M
MECHANISMS OF ARSENIC TRANSPORT AND BIOTRANSFORMATIONSR35GM136211 · NIGMS · FLORIDA INTERNATIONAL UNIVERSITY · PI ROSEN, BARRY P. · 2020 to 2024
$2.3M
SUBSTRATE RECOGNITION IN MULTIDRUG RESISTANCER01GM052216 · NIGMS · WAYNE STATE UNIVERSITY · PI ROSEN, BARRY P. · 1995 to 2008
$1.8M
The human arsenic methylation pathwayR01ES023779 · NIEHS · FLORIDA INTERNATIONAL UNIVERSITY · PI ROSEN, BARRY P. · 2015 to 2019
$1.6M
Austrian Science Fund FWF I 2412NIEHS NIH HHS R01 ES023779NIGMS NIH HHS R01 GM052216NIGMS NIH HHS R01 GM055425NIGMS NIH HHS R35 GM136211
6 · The paper itself

Abstract

Arsenosugars are arsenic-containing ribosides that play a substantial role in arsenic biogeochemical cycles. Arsenosugars were identified more than 30 years ago, and yet their mechanism of biosynthesis remains unknown. In this study we report identification of the arsS gene from the cyanobacterium Synechocystis sp. PCC 6803 and show that it is involved in arsenosugar biosynthesis. In the Synechocystis sp. PCC 6803 ars operon, arsS is adjacent to the arsM gene that encodes an As(III) S-adenosylmethionine (SAM) methyltransferase. The gene product, ArsS, contains a characteristic CX

Indexed as

ArsenicSynechocystisArsenatesMonosaccharidesArsenatesArsenicarsenosugarMonosaccharides

Identifiers

PMID30525501
PMCPMC6467767
OpenAlexW2904201251

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.