Evidence map›Paper›PMID 30525446›Full record

ArticleACS nano2019

Fluorous-Soluble Metal Chelate for Sensitive Fluorine-19 Magnetic Resonance Imaging Nanoemulsion Probes.

Amin Haghighat Jahromi, Chao Wang, Stephen R Adams, Wenlian Zhu, Kazim Narsinh, Hongyan Xu, Danielle L Gray, Roger Y Tsien, Eric T Ahrens

Abstract read
In one paragraph

Article in ACS nano, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. TargetedJournal of nanobiotechnology · 2026
    Article
  2. Synthesis, Characterization, and Magnetic Properties of Fe(BIP)Pharmaceuticals (Basel, Switzerland) · 2026
    Article
  3. Review
  4. Review
  5. UltrasensitiveAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  6. Review
  7. Review
  8. Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  9. Article
  10. An Fe complex forChemical science · 2023
    Article
  11. Nanomaterial-based contrast agents.Nature reviews. Methods primers · 2023
    Article
  12. Multinuclear MRI in Drug Discovery.Molecules (Basel, Switzerland) · 2022
    Review
  13. Article
  14. An ActivatableChemistryOpen · 2022
    Article
  15. Article
  16. Review
  17. ChemMedChem · 2022
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Amin Haghighat JahromiDepartment of Radiology , University of California, San Diego , La Jolla , California 92093 , United States.
Chao WangDepartment of Radiology , University of California, San Diego , La Jolla , California 92093 , United States.ORCID 0000-0002-0014-1976
Stephen R AdamsDepartment of Pharmacology , University of California, San Diego , La Jolla , California 92093 , United States.ORCID 0000-0002-4725-2091
Wenlian ZhuDepartment of Radiology , University of California, San Diego , La Jolla , California 92093 , United States.
Kazim NarsinhDepartment of Radiology , University of California, San Diego , La Jolla , California 92093 , United States.
Hongyan XuDepartment of Radiology , University of California, San Diego , La Jolla , California 92093 , United States.
Danielle L GraySchool of Chemical Sciences , University of Illinois at Urbana-Champaign , Urbana , Illinois 61801 , United States.ORCID 0000-0003-0059-2096
Roger Y TsienDepartment of Pharmacology , University of California, San Diego , La Jolla , California 92093 , United States.
Eric T AhrensDepartment of Radiology , University of California, San Diego , La Jolla , California 92093 , United States.ORCID 0000-0001-6131-9304

Funding

CLINICAL TRANSLATION OF 19F MRI TO VISUALIZE CANCER IMMUNOTHERAPEUTIC CELLSR01CA134633 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI AHRENS, ERIC T., COHEN, EZRA · 2009 to 2021
$4.4M
Traning Clinical Scientists in Radiological ImagingT32EB005970 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Eric Y Chang, Rebecca Ann Rakow-Penner · 2007 to 2026
$3.2M
Compositions and methods for enhanced fluorine-19 magnetic resonance imaging cell trackingR01EB024015 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI AHRENS, ERIC T. · 2017 to 2020
$2.3M
Intracellular oxygen sensing using 19F MRIR01EB017271 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI AHRENS, ERIC T. · 2013 to 2016
$1.3M
NCI NIH HHS R01 CA134633NIBIB NIH HHS R01 EB017271NIBIB NIH HHS R01 EB024015NIBIB NIH HHS T32 EB005970
6 · The paper itself

Abstract

Fluorine-19 MRI is an emerging cellular imaging approach, enabling lucid, quantitative "hot-spot" imaging with no background signal. The utility of

Indexed as

AnimalsCobaltContrast MediaEmulsionsEthylenediaminesFluorineFluorocarbonsGalliumIron Chelating AgentsMacrophagesMagnetic Resonance ImagingManganeseMetalsMiceCobaltContrast MediaEmulsionsEthylenediaminesFluorineFluorocarbonsGalliumIron Chelating AgentsManganeseMetals19Finflammationmacrophagemetal chelateMRInanoemulsionperfluorocarbon

Identifiers

PMID30525446
PMCPMC6467752

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.