ReviewJornal brasileiro de nefrologia
Bone biopsy in nephrology practice.
Review in Jornal brasileiro de nefrologia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
13 citing papers in PubMed, 19 citations in OpenAlex.
- Pathophysiology of chronic kidney disease-mineral bone disorder (CKD-MBD): from adaptive to maladaptive mineral homeostasis.Clinical kidney journal · 2025Article
- Evanescent extraosseous calcifications in low turnover bone: management and outcomes: a case report.Frontiers in nephrology · 2025Article
- Adiposity and Mineral Balance in Chronic Kidney Disease.Current osteoporosis reports · 2024Review
- Osteoporosis in Renal Disease.Indian journal of orthopaedics · 2023Review
- Article
- Osteoporosis, an Inevitable Circumstance of Chronic Kidney Disease: A Systematic Review.Cureus · 2021Review
- Effects of Analgesics on Tumor Growth in Mouse Models of Prostate Cancer Bone Metastasis.Journal of the American Association for Laboratory Animal Science : JAALAS · 2021Article
- Article
- The role of uric acid in mineral bone disorders in chronic kidney disease.Journal of nephrology · 2019Review
- Renal osteodystrophy in Brazil: the skeleton calls for greater attention!Jornal brasileiro de nefrologiaArticle
- Diagnosis of bone abnormalities in CKD-MBD (Imaging and bone biopsy).Jornal brasileiro de nefrologiaArticle
- Renal osteodystrophy in a sample of patients on dialysis in Northeastern Brazil: a cross-sectional analysis.Jornal brasileiro de nefrologiaArticle
- Treatment of Osteoporosis in Chronic Kidney Disease.Jornal brasileiro de nefrologiaArticle
Corrections and comments
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Authors and funding
4 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Renal osteodystrophy (ROD), a group of metabolic bone diseases secondary to chronic kidney disease (CKD), still represents a great challenge to nephrologists. Its management is tailored by the type of bone lesion - of high or low turnover - that cannot be accurately predicted by serum biomarkers of bone remodeling available in daily clinical practice, mainly parathyroid hormone (PTH) and alkaline phosphatase (AP). In view of this limitation, bone biopsy followed by bone quantitative histomorphometry, the gold-standard method for the diagnosis of ROD, is still considered of paramount importance. Bone biopsy has also been recommended for evaluation of osteoporosis in the CKD setting to help physicians choose the best anti-osteoporotic drug. Importantly, bone biopsy is the sole diagnostic method capable of providing dynamic information on bone metabolism. Trabecular and cortical bones may be analyzed separately by evaluating their structural and dynamic parameters, thickness and porosity, respectively. Deposition of metals, such as aluminum and iron, on bone may also be detected. Despite of these unique characteristics, the interest on bone biopsy has declined over the last years and there are currently few centers around the world specialized on bone histomorphometry. In this review, we will discuss the bone biopsy technique, its indications, and the main information it can provide. The interest on bone biopsy should be renewed and nephrologists should be capacitated to perform it as part of their training during medical residency.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.