Evidence map›Paper›PMID 30524946›Full record

ArticleFEBS open bio2018

Interleukin-18 expression in oral squamous cell carcinoma: its role in tumor cell migration and invasion, and growth of tumor cell xenografts.

Yuyang Li, Zhiming Xu, Jia Li, Shuofeng Ban, Congcong Duan, Weiwei Liu

Open access · goldAbstract read
In one paragraph

Article in FEBS open bio, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Senescent thyroid tumor cells promote their migration by inducing the polarization of M2-like macrophages.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2021
    Article
  10. Overexpression of gasdermin D promotes invasion of adenoid cystic carcinoma.International journal of clinical and experimental pathology · 2020
    Article
  11. Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yuyang LiDepartment of Dental Implantology School and Hospital of Stomatology Jilin University Jilin Provincial Key Laboratory of Tooth Development and Bone Remodeling Changchun Jilin China.
Zhiming XuDepartment of Oral and Maxillofacial Surgery School and Hospital of Stomatology Jilin University Jilin Provincial Key Laboratory of Tooth Development and Bone Remodeling Changchun Jilin China.
Jia LiDepartment of Oral and Maxillofacial Surgery School and Hospital of Stomatology Jilin University Jilin Provincial Key Laboratory of Tooth Development and Bone Remodeling Changchun Jilin China.
Shuofeng BanDepartment of Oral and Maxillofacial Surgery School and Hospital of Stomatology Jilin University Jilin Provincial Key Laboratory of Tooth Development and Bone Remodeling Changchun Jilin China.
Congcong DuanDepartment of Oral and Maxillofacial Surgery School and Hospital of Stomatology Jilin University Jilin Provincial Key Laboratory of Tooth Development and Bone Remodeling Changchun Jilin China.
Weiwei LiuDepartment of Oral and Maxillofacial Surgery School and Hospital of Stomatology Jilin University Jilin Provincial Key Laboratory of Tooth Development and Bone Remodeling Changchun Jilin China.
Jilin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oral squamous cell carcinoma (OSCC) is one of the most common head and neck malignancies. Advanced stages of the disease are associated with poor survival, highlighting a need for new treatment modalities. We previously showed that the proinflammatory cytokine interleukin-18 (IL-18) has a tumor suppressive role in OSCC. Here, we investigated the effects of IL-18 on proliferation, migration, and invasion of OSCC cells

Indexed as

growthIL‐18interleukin‐18migration and invasionoral squamous cell carcinomaxenograft model

Identifiers

PMID30524946
PMCPMC6275252
OpenAlexW2892906920

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.