ArticleBMC obesity2018
Tranexamic acid therapy for postoperative bleeding after bariatric surgery.
Article in BMC obesity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07098780 (Role of Tranexamic Acid in Reducing Hemorrhagic Events in Bariatric Surgery), which is not on this map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Role of Tranexamic Acid in Reducing Hemorrhagic Events in Bariatric Surgery
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- Effectiveness of Prophylactic Doses of Tranexamic Acid in Reducing Hemorrhagic Events in Bariatric Surgery: A Systematic Review and Meta-Analysis.Obesity surgery · 2026Pooled it
- Efficacy and Safety of Tranexamic Acid in Sleeve Gastrectomy: A Double-Blind Randomized Controlled Trial.Obesity surgery · 2026Trial
- Peroperative administration of tranexamic acid in sleeve gastrectomy to reduce hemorrhage: a double-blind randomized controlled trial.Surgical endoscopy · 2023Trial
- Tranexamic acid effects in postoperative bleeding outcomes in laparoscopic sleeve gastrectomy: a controlled study.Acta cirurgica brasileira · 2022Trial
- Prophylactic Tranexamic Acid as Prevention for Early Postoperative Bleeding after Roux-en-Y Gastric Bypass.Obesity surgery · 2026Article
- Racial and Ethnic Disparities in Causes for Reoperation and Reintervention Following Bariatric Surgery.Journal of racial and ethnic health disparities · 2026Article
- Effectiveness of Tranexamic Acid in Reducing Hidden Blood Loss During Laparoscopic Sleeve Gastrectomy: A Randomized Clinical Trial.Journal of clinical medicine · 2025Article
- Unraveling Postoperative Bleeding Dynamics in Laparoscopic Roux-en-Y Gastric Bypass: Insights from a Single-Center Tranexamic Acid Study.Obesity surgery · 2024Article
- Article
- The Role of Tranexamic Acid in Sleeve Gastrectomy: A Systematic Review and Meta-Analysis.Cureus · 2024Review
- Article
- Timing and management of bleeding after bariatric surgery.Surgical endoscopy · 2023Article
- Effectiveness of prophylactic doses of tranexamic acid in reducing hemorrhagic events in sleeve gastrectomy.Langenbeck's archives of surgery · 2022Article
- Preoperative risk factors for early hemorrhagic complications in bariatric surgery: a case-control study.Surgical endoscopy · 2022Article
- Bilateral pulmonary embolism while receiving tranexamic acid: a case report.Journal of medical case reports · 2020Article
- [Risk factors for nausea and vomiting after adolescent idiopathic scoliosis surgery].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2020Article
- Article
- A Single-Center Comparison of Extended and Restricted THROMBOPROPHYLAXIS with LMWH after Metabolic Surgery.Obesity surgery · 2020Article
- Suspected anaphylactic shock associated with administration of tranexamic acid in a dog.The Journal of veterinary medical science · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTranexamic acid reduces blood loss associated with various surgical procedures. Postoperative bleeding caused by dissection or bleeding of the enteric staple lines is a well-known complication following bariatric surgery. Reoperation in order to restore hemostasis is frequently necessary (up to 2.5% in literature). The effect of conservative therapy using tranexamic acid for postoperative hemorrhage after bariatric surgery is still very much a novel technique. The aim is to present our results (reoperation rate and thrombo-embolic complication rate) of tranexamic acid therapy for postoperative bleeding after bariatric surgery in comparison to those in existing literature.
methodsWe retrospectively reviewed 1388 patients who underwent bariatric surgery (laparoscopic gastric bypass or laparoscopic gastric sleeve). Use of tranexamic acid, reoperation rate, transfusion rate and rate of thrombo-embolic complications were reviewed.
resultsForty-five of 1388 (3.2%) total patients experienced significant hemorrhage after bariatric surgery. Tranexamic acid was administered in 44 of these patients. A failure of the treatment with tranexamic acid was observed in four patients. The incidence of reoperation was 0.4% for the entire population. No thrombo-embolic complications were registered for patients receiving tranexamic acid.
conclusionThese findings suggest that the administration of tranexamic acid appears to be safe in reducing the reoperation rate for bleeding after bariatric surgery.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.