Evidence map›Paper›PMID 30524724›Full record

ArticleClinical kidney journal2018

Peritoneal dialysis fluid biocompatibility impact on human peritoneal membrane permeability.

Francisco Rodríguez-Esparragón, Silvia Marrero-Robayna, Fayna González-Cabrera, Yaridé Hernández-Trujillo, Nisa Buset-Ríos, José Carlos Rodríguez-Pérez, Nicanor Vega-Díaz

Open access · goldAbstract read
In one paragraph

Article in Clinical kidney journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 90% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Francisco Rodríguez-EsparragónUnidad de Investigación, Hospital Universitario de Gran Canaria Dr Negrín, Las Palmas de Gran Canaria, Gran Canaria, Spain.
Silvia Marrero-RobaynaUnidad de Investigación, Hospital Universitario de Gran Canaria Dr Negrín, Las Palmas de Gran Canaria, Gran Canaria, Spain.
Fayna González-CabreraUnidad de Investigación, Hospital Universitario de Gran Canaria Dr Negrín, Las Palmas de Gran Canaria, Gran Canaria, Spain.
Yaridé Hernández-TrujilloUnidad de Investigación, Hospital Universitario de Gran Canaria Dr Negrín, Las Palmas de Gran Canaria, Gran Canaria, Spain.
Nisa Buset-RíosUnidad de Investigación, Hospital Universitario de Gran Canaria Dr Negrín, Las Palmas de Gran Canaria, Gran Canaria, Spain.
José Carlos Rodríguez-PérezUnidad de Investigación, Hospital Universitario de Gran Canaria Dr Negrín, Las Palmas de Gran Canaria, Gran Canaria, Spain.
Nicanor Vega-DíazUnidad de Investigación, Hospital Universitario de Gran Canaria Dr Negrín, Las Palmas de Gran Canaria, Gran Canaria, Spain.
Hospital Universitario de Gran Canaria Doctor Negrín · ESUniversidad de Las Palmas de Gran Canaria · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe have compared the effects of conventional lactate-based peritoneal dialysis fluid (CPDF) with respect to bicarbonate/lactate-based fluid on peritoneal ultrafiltration (UF) and peritoneal permeability, and on variations on gene expression in cells isolated from effluents of patients' peritoneal bags.

methodsThis was a non-randomized sequential prospective study including all incident peritoneal dialysis (PD) patients (

resultsIn the overall study, the use of BPDF was associated with significantly lower mass transfer area coefficient for urea and creatinine, longer accelerated peritoneal examination test times for urea and creatinine, lower total pore area available for exchange over diffusion distance and lower UF. There were no differences in the gene expression of

conclusionThis study shows that those patients who started PD treatment with BPDF were characterized by a better biocompatibility profile. BPDF associates with lower peritoneal permeability to small molecules and lower UF.

Indexed as

bicarbonate/lactate buffered solutionbiocompatibilityepithelial-to-mesenchymal transitionmesothelial cellsperitoneal dialysisperitoneal transport rate

Identifiers

PMID30524724
PMCPMC6275447
OpenAlexW2811029770

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.