Evidence map›Paper›PMID 30524711›Full record

ArticleClinical kidney journal2018

Treatment of multiple myeloma with renal involvement: the nephrologist's view.

Alexandre Favà, Xavier Fulladosa, Nuria Montero, Juliana Draibe, Joan Torras, Montse Gomà, Josep M Cruzado

Open access · goldAbstract read
In one paragraph

Article in Clinical kidney journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Alexandre FavàNephrology Department, Hospital Universitari de Bellvitge, Idibell, Barcelona, Spain.
Xavier FulladosaNephrology Department, Hospital Universitari de Bellvitge, Idibell, Barcelona, Spain.
Nuria MonteroNephrology Department, Hospital Universitari de Bellvitge, Idibell, Barcelona, Spain.
Juliana DraibeNephrology Department, Hospital Universitari de Bellvitge, Idibell, Barcelona, Spain.
Joan TorrasNephrology Department, Hospital Universitari de Bellvitge, Idibell, Barcelona, Spain.
Montse GomàPathology Department, Hospital Universitari de Bellvitge, Idibell, Barcelona, Spain.
Josep M CruzadoNephrology Department, Hospital Universitari de Bellvitge, Idibell, Barcelona, Spain.
Bellvitge University Hospital · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Renal injury is a common complication in multiple myeloma (MM). In fact, as many as 10% of patients with MM develop dialysis-dependent acute kidney injury related to increased free light chain (FLC) production by a plasma cell clone. Myeloma cast nephropathy (MCN) is the most prevalent pathologic diagnosis associated with renal injury, followed by light chain deposition disease and light chain amyloidosis. Several FLC removal techniques have been explored to improve kidney disease in MM but their impact on renal clinical outcomes remains unclear. According to the evidence, high cut-off haemodialysis should be restricted to MM patients on chemotherapy with histological diagnosis of MCN and haemodialysis requirements. From our perspective, more efforts are needed to improve kidney outcomes in patients with MM and renal failure.

Indexed as

acute renal failurefree light chainshigh cut-off haemodialysismyeloma cast nephropathyplasmapheresis

Identifiers

PMID30524711
PMCPMC6275441
OpenAlexW2886540745

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.