Evidence map›Paper›PMID 30524424›Full record

Trial reportFrontiers in immunology2018

Baseline Gastrointestinal Eosinophilia Is Common in Oral Immunotherapy Subjects With IgE-Mediated Peanut Allergy.

Benjamin L Wright, Nielsen Q Fernandez-Becker, Neeraja Kambham, Natasha Purington, Dana Tupa, Wenming Zhang, Matthew A Rank, Hirohito Kita, Kelly P Shim, Bryan J Bunning and 9 more

Open access · goldAbstract readClinical Trial, Phase IIRandomized Controlled Trial
In one paragraph

Trial report in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 1 pooled it
6.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 1 synthesis or guideline pooled it, 67 citations in OpenAlex.

  1. Pooled it
  2. Gastrointestinal Eosinophil Responses in a Longitudinal, Randomized Trial of Peanut Oral Immunotherapy.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2021
    Trial
  3. Trial
  4. Gastrointestinal manifestations during oral immunotherapy: A guide for pediatric allergists.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2026
    Review
  5. Article
  6. Asymptomatic esophageal eosinophilia in oral immunotherapy: context and clinical application.The journal of allergy and clinical immunology. In practice · 2026
    Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Review
  17. The Relationship Between Eosinophilic Esophagitis and Immunotherapy.Immunology and allergy clinics of North America · 2024
    Review
  18. Review
  19. A case of food and aeroallergen sublingual immunotherapy inducing eosinophilic esophagitis.The journal of allergy and clinical immunology. Global · 2023
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 5 institutions in 1 country.

Benjamin L WrightDivision of Allergy, Asthma, and Clinical Immunology, Department of Medicine, Mayo Clinic Arizona, Scottsdale, AZ, United States.
Nielsen Q Fernandez-BeckerSean N. Parker Center for Allergy and Asthma Research, Stanford University School of Medicine, Stanford, CA, United States.
Neeraja KambhamSean N. Parker Center for Allergy and Asthma Research, Stanford University School of Medicine, Stanford, CA, United States.
Natasha PuringtonSean N. Parker Center for Allergy and Asthma Research, Stanford University School of Medicine, Stanford, CA, United States.
Dana TupaSean N. Parker Center for Allergy and Asthma Research, Stanford University School of Medicine, Stanford, CA, United States.
Wenming ZhangSean N. Parker Center for Allergy and Asthma Research, Stanford University School of Medicine, Stanford, CA, United States.
Matthew A RankDivision of Allergy, Asthma, and Clinical Immunology, Department of Medicine, Mayo Clinic Arizona, Scottsdale, AZ, United States.
Hirohito KitaDivision of Allergic Diseases, Internal Medicine, Mayo Clinic, Rochester, MN, United States.
Kelly P ShimDivision of Pulmonology, Phoenix Children's Hospital, Phoenix, AZ, United States.
Bryan J BunningSean N. Parker Center for Allergy and Asthma Research, Stanford University School of Medicine, Stanford, CA, United States.
Alfred D DoyleDivision of Allergy, Asthma, and Clinical Immunology, Department of Medicine, Mayo Clinic Arizona, Scottsdale, AZ, United States.
Elizabeth A JacobsenDivision of Allergy, Asthma, and Clinical Immunology, Department of Medicine, Mayo Clinic Arizona, Scottsdale, AZ, United States.
Scott D BoydSean N. Parker Center for Allergy and Asthma Research, Stanford University School of Medicine, Stanford, CA, United States.
Mindy TsaiDepartment of Pathology, Stanford University School of Medicine, Stanford, CA, United States.
Holden MaeckerInstitute for Immunity, Transplantation, and Infection, Stanford University School of Medicine, Stanford, CA, United States.
Monali ManoharSean N. Parker Center for Allergy and Asthma Research, Stanford University School of Medicine, Stanford, CA, United States.
Stephen J GalliSean N. Parker Center for Allergy and Asthma Research, Stanford University School of Medicine, Stanford, CA, United States.
Kari C NadeauSean N. Parker Center for Allergy and Asthma Research, Stanford University School of Medicine, Stanford, CA, United States.
R Sharon ChinthrajahSean N. Parker Center for Allergy and Asthma Research, Stanford University School of Medicine, Stanford, CA, United States.
Stanford University · USPhoenix Children's Hospital · USWinnMed · USMayo Clinic · USMayo Clinic in Arizona · US

Funding

Tracking allergen specific T cells in multi-food allergyU19AI104209 · NIAID · STANFORD UNIVERSITY · PI GALLI, STEPHEN JOSEPH · 2013 to 2025
$17.3M
FUNCTIONAL ANALYSIS OF PATHOGENIC AND PROTECTIVE PEANUT ALLERGEN-SPECIFIC HUMAN ANTIBODIESR01AI125567 · NIAID · STANFORD UNIVERSITY · PI BOYD, SCOTT DEXTER · 2017 to 2022
$2.6M
NIAID NIH HHS R01 AI125567NIAID NIH HHS U19 AI104209
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Administration, OralAdultAllergensArachisDesensitization, ImmunologicDouble-Blind MethodEndoscopy, Digestive SystemEosinophiliaEosinophilsFemaleGastrointestinal TractHumansImmunoglobulin EMalePeanut HypersensitivitySurveys and QuestionnairesAllergensImmunoglobulin Eadverse eventbiopsyendoscopyeosinophilEosinophilic Esophagitisgastrointestinaloral immunotherapypeanut food allergy

Identifiers

PMID30524424
PMCPMC6261984
OpenAlexW2901509911

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.