ArticleFrontiers in behavioral neuroscience2018
Modulation of Fear and Arousal Behavior by Serotonin Transporter (5-HTT) Genotypes in Newly Hatched Chickens.
Article in Frontiers in behavioral neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 17 citations in OpenAlex.
- Exploratory Study on Individual Locomotor Activity in Local Dual-Purpose and Commercial Breeder Pullets.Animals : an open access journal from MDPI · 2023Article
- Increased dietary 5-hydroxytryptophan reduces fearfulness in red junglefowl hens (Frontiers in physiology · 2023Article
- Molecular biology of serotonergic systems in avian brains.Frontiers in molecular neuroscience · 2023Review
- Effect of prenatal different auditory environment on learning ability and fearfulness in chicks.Animal bioscience · 2022Article
- Chick Hippocampal Formation Displays Subdivision- and Layer-Selective Expression Patterns of Serotonin Receptor Subfamily Genes.Frontiers in physiology · 2022Article
- Brain gain-Is the cognitive performance of domestic hens affected by a functional polymorphism in the serotonin transporter gene?Frontiers in psychology · 2022Article
- Dopaminergic nuclei in the chick midbrain express serotonin receptor subfamily genes.Frontiers in physiology · 2022Article
- Maternal age and maternal environment affect stress reactivity and measures of social behaviour in laying hens.Scientific reports · 2021Article
- Evaluation of Euthanasia Methods on Behavioral and Physiological Responses of Newly Hatched Male Layer Chicks.Animals : an open access journal from MDPI · 2021Article
- Emotion Induced Monoamine Neuromodulator Release Affects Functional Neurological Disorders.Frontiers in cell and developmental biology · 2021Review
- Serotonergic Neurons in the Chick Brainstem Express Various Serotonin Receptor Subfamily Genes.Frontiers in physiology · 2021Article
- The dorsal arcopallium of chicks displays the expression of orthologs of mammalian fear related serotonin receptor subfamily genes.Scientific reports · 2020Article
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The serotonin transporter (5-HTT) plays a key role in regulating serotonergic transmission via removal of serotonin (5-hydroxytryptamine, 5-HT) from synaptic clefts. Alterations in 5-HTT expression and 5-HT transmission have been shown to cause changes to adult behavior including fear. The objective of the present study was to investigate the 5-HTT role in fear in birds at the very early stages of post-hatching life. Using an avoidance test with an elevated balance beam, which was based on depth perception and the respective fear of heights, we assessed fear-related avoidance behaviors of newly hatched chicks of the three functional 5-HTT genotypes W/W, W/D and D/D. Newly hatched chicks of the genotype D/D, which was linked to high 5-HTT expression, showed less intensive avoidance responses as measured by decreased latency to jump than W/W and W/D chicks. Further, significantly fewer D/D hens than W/W hens showed fear-like behavior that resembled a freezing response. Furthermore, in an arousal test the arousal reaction of the chicks in response to an acute short-term visual social deprivation in the home compartment was assessed 5 weeks after hatching, which also revealed that D/D chicks exhibited decreased arousal reaction, compared to W/W chicks. Thus, the results indicate that fear responses differ in D/D chicks in the early post-hatching periods, possibly due to the different expression of 5-HTT respectively 5-HT levels in this strain.
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