Evidence map›Paper›PMID 30524197›Full record

ArticleMediators of inflammation2018

Plasma Asprosin Levels Are Associated with Glucose Metabolism, Lipid, and Sex Hormone Profiles in Females with Metabolic-Related Diseases.

Xing Li, Mingyu Liao, Rufei Shen, Linlin Zhang, Hua Hu, Jun Wu, Xiuli Wang, Hua Qu, Shaodong Guo, Min Long and 1 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Mediators of inflammation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05951309 (Effect of Myoinositol on Serum Asprosin Levels in PCOS Patients), which is not on this map. Cited by 68 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed, 1 pooled it
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05951309 nacompletednot on this mapstarted 2021, after this paper: background citation

Effect of Myoinositol on Serum Asprosin Levels in PCOS Patients

TypeinterventionalSponsorNear East University, TurkeyRan2021 to 2023Enrolled30ConditionsPCOS, Insulin ResistanceArmsinofolic combi, Glucophage 500Mg Tablet
3 · Its place in the literature

Who cites it

68 citing papers in PubMed, 1 synthesis or guideline pooled it, 128 citations in OpenAlex.

  1. Pooled it
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  7. Review
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  12. Review
  13. Asprosin and Neuregulin 4 in Obesity in Children.Medicina (Kaunas, Lithuania) · 2025
    Article
  14. Article
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8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Xing LiDepartment of Endocrinology, Xinqiao Hospital, Third Military Medical University (Army Medical University), Chongqing 400037, China.
Mingyu LiaoDepartment of Endocrinology, Xinqiao Hospital, Third Military Medical University (Army Medical University), Chongqing 400037, China.
Rufei ShenDepartment of Endocrinology, Xinqiao Hospital, Third Military Medical University (Army Medical University), Chongqing 400037, China.
Linlin ZhangDepartment of Endocrinology, Xinqiao Hospital, Third Military Medical University (Army Medical University), Chongqing 400037, China.
Hua HuDepartment of Obstetrics and Gynecology, Xinqiao Hospital, Third Military Medical University (Army Medical University), Chongqing 400037, China.
Jun WuDepartment of Health Management, Xinqiao Hospital, Third Military Medical University (Army Medical University), Chongqing 400037, China.
Xiuli WangDepartment of Health Management, Xinqiao Hospital, Third Military Medical University (Army Medical University), Chongqing 400037, China.
Hua QuDepartment of Endocrinology, Xinqiao Hospital, Third Military Medical University (Army Medical University), Chongqing 400037, China.ORCID 0000-0002-4895-5979
Shaodong GuoDepartment of Nutrition and Food Science College of Agriculture and Life Sciences, Texas A&M University, Texas 77843, USA.
Min LongDepartment of Endocrinology, Xinqiao Hospital, Third Military Medical University (Army Medical University), Chongqing 400037, China.ORCID 0000-0003-1071-8131
Hongting ZhengDepartment of Endocrinology, Xinqiao Hospital, Third Military Medical University (Army Medical University), Chongqing 400037, China.ORCID 0000-0002-6930-0103
Army Medical University · CNTexas A&M University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Asprosin is a white adipose tissue-derived hormone that increases abnormally in mammals with insulin resistance. However, the role of asprosin in polycystic ovary syndrome (PCOS), a disease partly characterized by insulin resistance, and its potential connection with type 2 diabetes mellitus (T2DM) and PCOS has not been thoroughly elucidated to date. To investigate the association of asprosin with metabolic profiles, sex-related hormones, or inflammation in females with T2DM or PCOS, plasma asprosin and metabolic indicators were measured in 66 healthy females, 53 female patients with T2DM, and 41 patients with PCOS. Spearman's correlation analysis and binary logistic regression analysis models were used. Plasma asprosin was significantly higher in T2DM females than in healthy subjects (

Indexed as

AdipokinesBlood GlucoseDiabetes Mellitus, Type 2FastingFemaleFibrillin-1Glycated HemoglobinHumansLipid MetabolismLogistic ModelsMicrofilament ProteinsPeptide FragmentsPeptide HormonesPolycystic Ovary SyndromeRisk FactorsTestosteroneAdipokinesBlood GlucoseFBN1 protein, humanFibrillin-1Glycated Hemoglobinhemoglobin A1c protein, humanMicrofilament ProteinsPeptide FragmentsPeptide HormonesTestosterone

Identifiers

PMID30524197
PMCPMC6247534
OpenAlexW2900427520

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.