Evidence map›Paper›PMID 30524191›Full record

ArticleJournal of nanoparticle research : an interdisciplinary forum for nanoscale science and technology2018

Influence of size and surface capping on photoluminescence and cytotoxicity of gold nanoparticles.

Cecilia Fernández-Ponce, Juan P Muñoz-Miranda, Desiré M de Los Santos, Enrique Aguado, Francisco García-Cozar, Rocío Litrán

Abstract read
In one paragraph

Article in Journal of nanoparticle research : an interdisciplinary forum for nanoscale science and technology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Heterosubstituted Derivatives of PtPFPP for OBioconjugate chemistry · 2022
    Article
  5. Article
  6. Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Cecilia Fernández-Ponce1Department of Biomedicine, Biotechnology and Public Health, University of Cadiz, Cádiz, Spain.
Juan P Muñoz-Miranda1Department of Biomedicine, Biotechnology and Public Health, University of Cadiz, Cádiz, Spain.
Desiré M de Los Santos3Department of Physical Chemistry and Instituto de Microscopía Electronica y Materiales (IMEYMAT), University of Cádiz, Cádiz, Puerto Real Spain.
Enrique Aguado1Department of Biomedicine, Biotechnology and Public Health, University of Cadiz, Cádiz, Spain.
Francisco García-Cozar1Department of Biomedicine, Biotechnology and Public Health, University of Cadiz, Cádiz, Spain.
Rocío LitránInstitute of Biomedical Research Cádiz (INIBICA), Cádiz, Spain.ORCID 0000-0003-2116-5309

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hydrophilic and homogeneous sub-10 nm blue light-emitting gold nanoparticles (NPs) functionalized with different capping agents have been prepared by simple chemical routes. Structure, average, size, and surface characteristics of these NPs have been widely studied, and the stability of colloidal NP solutions at different pH values has been evaluated. Au NPs show blue PL emission, particularly in the GSH capped NPs, in which the thiol-metal core transference transitions considerably enhance the fluorescent emission. The influence of capping agent and NP size on cytotoxicity and on the fluorescent emission are analyzed and discussed in order to obtain Au NPs with suitable features for biomedical applications. Cytotoxicity of different types of gold NPs has been determined using NPs at high concentrations in both tumor cell lines and primary cells. All NPs used show high biocompatibility with low cytotoxicity even at high concentration, while Au-GSH NPs decrease viability and proliferation of both a tumor cell line and primary lymphocytes.

Indexed as

AgentCappingCell viabilityCytotoxicityGold nanoparticlesGSHPhotoluminescenceProliferationSemiconfocal microscopy

Identifiers

PMID30524191
PMCPMC6244783

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.