Evidence map›Paper›PMID 30524014›Full record

ArticlePhysics in medicine and biology2018

LET dependent response of GafChromic films investigated with MeV ion beams.

V Grilj, D J Brenner

Abstract read
In one paragraph

Article in Physics in medicine and biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. A review on radiochromic film dosimetry in radiation therapy.Journal of applied clinical medical physics · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Biological effects in normal cells exposed to FLASH dose rate protons.Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

V GriljCenter for Radiological Research, Columbia University Irving Medical Center, New York, NY, United States of America.ORCID 0000-0001-6573-8063
D J BrennerCenter for Radiological Research, Columbia University Irving Medical Center, New York, NY, United States of America.

Funding

TR&D 3P41EB002033 · NIBIB · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BRENNER, DAVID JONATHAN · 2003 to 2018
$17.0M
NIBIB NIH HHS P41 EB002033
6 · The paper itself

Abstract

The change in optical properties of GafChromic films depends not only on the absorbed dose, but also on the linear energy transfer (LET) of the ionizing radiation. The influence of LET on the film dose-response relationship is especially important when films are applied for dosimetry of energetic charged particles. In the present study, we examined the response of the unlaminated EBT3 and MD-V3 films to proton, deuterium and helium beams with energies in the range of several megaelectronvolts (MeV). Films were exposed to doses up to 200 Gy and a model based on the bimolecular chemical reaction was chosen to fit the measured film signals. The LET in the active layers of the films and the dose correction factors were computed with Monte Carlo software TRIM. Signal quenching, observed for all ion beams in comparison to x-rays, was investigated as a function of the LET in the range of 10-100 keV µm

Indexed as

Linear Energy TransferModels, TheoreticalFilm DosimetryRadiation Dosage

Identifiers

PMID30524014
PMCPMC7586727

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.