Evidence map›Paper›PMID 30523567›Full record

ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2019

A note on the relationship between age and health-related quality of life assessment.

Patricia Cubi-Molla, Koonal Shah, Jamie Garside, Mike Herdman, Nancy Devlin

Abstract read
In one paragraph

Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Preferences for health-related quality of life: do they vary by age? A systematic literature review on the EQ-5D measure.The European journal of health economics : HEPAC : health economics in prevention and care · 2025
    Pooled it
  2. Article
  3. Article
  4. Completing the time trade-off with respondents who are older, in poorer health or with an immigrant background in an EQ-5D-5L valuation study.The European journal of health economics : HEPAC : health economics in prevention and care · 2023
    Article
  5. Time trade-off with someone to live for: impact of having significant others on time trade-off valuations of hypothetical health states.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Patricia Cubi-MollaThe Office of Health Economics, London, UK. pcubi-molla@ohe.org.ORCID http://orcid.org/0000-0002-2803-7337
Koonal ShahThe Office of Health Economics, London, UK.ORCID http://orcid.org/0000-0002-4927-7858
Jamie GarsideJanssen, High Wycombe, UK.
Mike HerdmanThe Office of Health Economics, London, UK.
Nancy DevlinThe Office of Health Economics, London, UK.ORCID http://orcid.org/0000-0002-1561-5361

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo extend existing analyses of whether and how the age of respondents is related to their time trade-off (TTO) valuations of hypothetical EQ-5D-3L health states, and to contribute to the existing debate about the rationale and implications for using age-specific utilities in health technology assessment (HTA).

methodsWe use data from the MVH UK valuation study. For each profile, the mean TTO value-adjusted by sex, education, self-reported health and personal experience of serious illness-is pairwise compared across the different age groups. A Bonferroni correction is applied to the multiple testing of significant differences between means. Smile plots illustrate the results. A debate regarding whether there is a case for using age-specific utilities in HTAs complements the analysis.

resultsResults show that the oldest respondents value health profiles lower than younger age groups, particularly for profiles describing problems in the mobility dimension.

conclusionThe findings raise the possibility of using age-specific value sets in HTAs, since a technology may not be cost-effective on average but cost-effective for a sub-group whose preferences are more closely aligned to the benefits offered by the technology.

Indexed as

AgedAge FactorsFemaleHumansMaleMiddle AgedQuality of LifeSurveys and QuestionnairesAge groupAge-specific value setEQ-5D profilesHTA decision-makingSmile plotSocial preferencesTime trade-off

Identifiers

PMID30523567
PMCPMC6470117

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.