Evidence map›Paper›PMID 30523498›Full record

ArticleCardiovascular toxicology2019

Cobalt Administration Causes Reduced Contractility with Parallel Increases in TRPC6 and TRPM7 Transporter Protein Expression in Adult Rat Hearts.

Sarunya Laovitthayanggoon, Catherine J Henderson, Claire McCluskey, Margaret MacDonald, Rothwelle J Tate, M Helen Grant, Susan Currie

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cardiovascular toxicology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. CaBiomedicines · 2025
    Review
  2. Cardiotoxicity concerns in total joint arthroplasty.World journal of orthopedics · 2024
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Sarunya LaovitthayanggoonDepartment of Biomedical Engineering, University of Strathclyde, Glasgow, G4 0RE, Scotland, UK.
Catherine J HendersonDepartment of Biomedical Engineering, University of Strathclyde, Glasgow, G4 0RE, Scotland, UK.
Claire McCluskeyStrathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, G4 0RE, Scotland, UK.
Margaret MacDonaldStrathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, G4 0RE, Scotland, UK.
Rothwelle J TateStrathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, G4 0RE, Scotland, UK.
M Helen GrantDepartment of Biomedical Engineering, University of Strathclyde, Glasgow, G4 0RE, Scotland, UK.
Susan CurrieStrathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, G4 0RE, Scotland, UK. susan.currie@strath.ac.uk.ORCID 0000-0002-4237-4428
University of Strathclyde · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exposure to circulating cobalt (Co

Indexed as

AnimalsCardiotoxicityCells, CulturedCobaltFibroblastsHeart DiseasesHeart VentriclesMaleMyocardial ContractionRats, Sprague-DawleySignal TransductionTime FactorsTRPC Cation ChannelsTRPM Cation ChannelsUp-RegulationVentricular Function, LeftCobaltcobaltous chlorideTrpc6 protein, ratTRPC Cation ChannelsTrpm7 protein, ratTRPM Cation ChannelsCardiac fibroblastCardiotoxicityCobaltDivalent metal transporter channel 1 (DMT1)Transient receptor potential (TRP) channels

Identifiers

PMID30523498
PMCPMC6505488
OpenAlexW2903894502

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.