ArticleHypertension research : official journal of the Japanese Society of Hypertension2019
Association of blood pressure with estimates of 24-h urinary sodium and potassium excretion from repeated single-spot urine samples.
Article in Hypertension research : official journal of the Japanese Society of Hypertension, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
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Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 30 citations in OpenAlex.
- Further evidence that methods based on spot urine samples should not be used to examine sodium-disease relationships from the Science of Salt: A regularly updated systematic review of salt and health outcomes (November 2018 to August 2019).Journal of clinical hypertension (Greenwich, Conn.) · 2020Pooled it
- Dietary Sodium Intake and Health Indicators: A Systematic Review of Published Literature between January 2015 and December 2019.Advances in nutrition (Bethesda, Md.) · 2020Pooled it
- A Randomized Clinical Trial of ICT-based Interventions for Sodium and Potassium Regulation in Healthy Adults.American journal of hypertension · 2025Trial
- Regional effect of population-based programs promoting salt reduction and potassium intake in Hokkaido: a post hoc analysis of the PoSPIP.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Article
- Are changes in the urinary sodium-to-potassium ratio associated with changes in blood pressure in a healthy population with low urinary sodium-to-potassium ratios? Eight-year follow-up results from the KOBE Study.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Article
- Current hypertension epidemiology and contemporary approaches using the "Real-World Evidence Cycle" framework.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Review
- Association between urinary sodium-to-potassium ratio and BNP in a general population without antihypertensive treatment and cardiovascular diseases: the Ohasama study.Hypertension research : official journal of the Japanese Society of Hypertension · 2025Article
- Association between sodium and potassium intake levels and body compositions of Chinese college students.Asia Pacific journal of clinical nutrition · 2023Article
- Association between the extent of house collapse and urine sodium-to-potassium ratio of victims affected by the 2011 Great East Japan Earthquake and Tsunami: a cross-sectional study.Hypertension research : official journal of the Japanese Society of Hypertension · 2023Article
- Latest hypertension research to inform clinical practice in Asia.Hypertension research : official journal of the Japanese Society of Hypertension · 2022Article
- Seven-action approaches for the management of hypertension in Asia - The HOPE Asia network.Journal of clinical hypertension (Greenwich, Conn.) · 2022Review
- Association between 24-h urinary sodium and potassium excretion and blood pressure among Chinese adults aged 18-69 years.Scientific reports · 2021Article
- Salt intake and blood pressure in Iranian children and adolescents: a population-based study.BMC cardiovascular disorders · 2021Article
- Article
- Dietary Potassium Intake Remains Low and Sodium Intake Remains High, and Most Sodium is Derived from Home Food Preparation for Chinese Adults, 1991-2015 Trends.The Journal of nutrition · 2020Article
- Multiple measurements of the urinary sodium-to-potassium ratio strongly related home hypertension: TMM Cohort Study.Hypertension research : official journal of the Japanese Society of Hypertension · 2020Article
- Comparison of 24-h Diet Records, 24-h Urine, and Duplicate Diets for Estimating Dietary Intakes of Potassium, Sodium, and Iodine in Children.Nutrients · 2019Article
- Urinary sodium-to-potassium ratio and intake of sodium and potassium among men and women from multiethnic general populations: the INTERSALT Study.Hypertension research : official journal of the Japanese Society of Hypertension · 2019Article
- Nutritional Risk Factors in Albuminuria and Retinopathy in Patients Newly Diagnosed With Type 2 Diabetes: A Cross-sectional Case Series Study.In vivo (Athens, Greece)Article
Corrections and comments
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Authors and funding
12 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
While the association between 24-h urinary sodium and potassium excretion with blood pressure is well established, the relationships of these ions to spot urine measurements are unclear. Our purpose is to assess the association between blood pressure and the estimated 24-h sodium and potassium excretion from repeated single-spot urine samples. Spot urine and blood pressure were collected annually during a 5-year period from 4360 Japanese workers with ages ranging from 19 to 55 years. Estimates of 24-h sodium and potassium excretion were based on Tanaka's formula. Overall, a single standard deviation increase in the estimated sodium excretion (36.5 mmol/day) was associated with a 1.3 mmHg higher systolic blood pressure and a 0.8 mmHg higher diastolic blood pressure (P < 0.001). A single standard deviation increase in estimated potassium excretion (8.9 mmol/day) was associated with a 1.1 mmHg lower systolic blood pressure and a 0.7 mmHg lower diastolic blood pressure (P < 0.001). As a combined measure of the excretion of both electrolytes, the estimated 24-h sodium-to-potassium ratio was positively associated with both blood pressures (P < 0.001). Associations of blood pressure with sodium and the sodium-to-potassium ratio increased with age and were stronger in men compared to women. Associations with potassium and the sodium-to-potassium ratio were stronger in individuals who were overweight. The findings provide evidence for an association between blood pressure and the estimated 24-h sodium and potassium excretion from repeated single-spot urine samples. As convenient measures of dietary intake for each electrolyte, repeated spot urine samples may be useful for assessing hypertension risk, especially in men, older individuals, and overweight individuals.
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