ArticleNature communications2018
Real-time determination of enantiomeric and isomeric content using photoelectron elliptical dichroism.
Article in Nature communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- Spectroscopy and Conformer-Selective Photoelectron Circular Dichroism of Chiral Molecules.Chemistry, an Asian journal · 2026Review
- Linking photoelectron circular dichroism to the asymmetric total photoemission yield measured in aerosol nanoparticles of tyrosine.Nature communications · 2026Article
- Excited State Assignment and State-Resolved Photoelectron Circular Dichroism in Chalcogen-Substituted Fenchones.Chemphyschem : a European journal of chemical physics and physical chemistry · 2025Article
- Determination of the Molar Fraction and Enantiomeric Excess of Electrosprayed Amino Acid Anions Employing Photoelectron Circular Dichroism.Analytical chemistry · 2025Article
- Tailoring full-Stokes thermal emission from twisted-gratings structures.Nanophotonics (Berlin, Germany) · 2024Article
- Determination of Enantiomeric Excess by Optofluidic Microlaser near Exceptional Point.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Induced photoelectron circular dichroism onto an achiral chromophore.Nature communications · 2023Article
- Ultrafast control over chiral sum-frequency generation.Science advances · 2023Article
- Tilting light's polarization plane to spatially separate the ultrafast nonlinear response of chiral molecules.Nanophotonics (Berlin, Germany) · 2023Article
- Fast and precise chiroptical spectroscopy by photoelectron elliptical dichroism.Physical chemistry chemical physics : PCCP · 2023Article
- A portable elliptical dichroism spectrometer targeting secondary structural features of tumorous protein for pancreatic cancer detection.Biosensors & bioelectronics · 2023Article
- Carrier envelope phase sensitivity of photoelectron circular dichroism.Physical chemistry chemical physics : PCCP · 2023Article
- Femtosecond photoelectron circular dichroism of chemical reactions.Science advances · 2022Article
- Absolute optical chiral analysis using cavity-enhanced polarimetry.Science advances · 2022Article
- Assignment-free chirality detection in unknown samples via microwave three-wave mixing.Communications chemistry · 2022Article
- Multi-photon above threshold ionization of multi-electron atoms and molecules using the R-matrix approach.Scientific reports · 2021Article
- Conformer-dependent vacuum ultraviolet photodynamics and chiral asymmetries in pure enantiomers of gas phase proline.Communications chemistry · 2021Article
- Rapid chiral analysis based on liquid-phase cyclic chemiluminescence.Chemical science · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The fast and accurate analysis of chiral chemical mixtures is crucial for many applications but remains challenging. Here we use elliptically-polarized femtosecond laser pulses at high repetition rates to photoionize chiral molecules. The 3D photoelectron angular distribution produced provides molecular fingerprints, showing a strong forward-backward asymmetry which depends sensitively on the molecular structure and degree of ellipticity. Continuously scanning the laser ellipticity and analyzing the evolution of the rich, multi-dimensional molecular signatures allows us to observe real-time changes in the chemical and chiral content present with unprecedented speed and accuracy. We measure the enantiomeric excess of a compound with an accuracy of 0.4% in 10 min acquisition time, and follow the evolution of a mixture with an accuracy of 5% with a temporal resolution of 3 s. This method is even able to distinguish isomers, which cannot be easily distinguished by mass-spectrometry.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.