ArticleScience (New York, N.Y.)2018
A DNA methylation reader complex that enhances gene transcription.
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Article in Science (New York, N.Y.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 144 papers.
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144citing papers in PubMed
10.1field-weighted citation impact, top 1% of its field
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Who cites it
144 citing papers in PubMed, 255 citations in OpenAlex.
- Investigation of allele-specific expression in citrus hybrids reveals the association between siRNA-mediatedHorticulture research · 2026Article
- Gene regulatory mechanisms downstream of DNA methylation.Nature reviews. Genetics · 2026Review
- Repeated drought induces a reproducible DNA methylation response associated with gene expression inbioRxiv : the preprint server for biology · 2026Article
- Transgenerational somatic mutations and epigenetic imprints on selected DNA repair gene promoters in Arabidopsis thaliana due to pesticides.Plant biology (Stuttgart, Germany) · 2026Article
- Analysis of deep-resequencing data of 984 soybean accessions reveals structural variations underlying agronomic traits.Nature communications · 2026Article
- Occupancy-based mechanism is the chief mode of ROS1 function in preventing DNA hypermethylation.Nature plants · 2026Article
- Integrated epigenomic and transcriptional profiling reveals genotype-specific adaptive reprogramming to drought stress in Brassica napus.BMC plant biology · 2026Article
- Genome-wide DNA methylation landscape and its association with the transcriptome reprogramming in potato in response toHorticulture research · 2026Article
- SHH1 cooperates with the DNA methylation reader MBD7 to suppress transcriptional silencing of promoter-methylated genes in Arabidopsis.Plant communications · 2026Article
- Epigenetic control of seed development and dormancy in cereals.Plant signaling & behavior · 2025Review
- DNA methylation contributes to plant acclimation to naturally fluctuating light.The New phytologist · 2025Article
- A Modular and Customizable CRISPR/Cas Toolkit for Epigenome Editing of Cis-regulatory Modules.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- An antagonistic epigenetic mechanism regulating gene expression in pollen revealed through single-nucleus multiomics.Nature communications · 2025Article
- Methylome-driven regulation of miRNA expression and its relationship to cardiac dysfunction in idiopathic dilated cardiomyopathy.Clinical epigenetics · 2025Article
- An antagonistic epigenetic mechanism regulating gene expression in pollen revealed through single-nucleus multiomics.bioRxiv : the preprint server for biology · 2025Article
- Spatiotemporal methylome remodeling during fiber differentiation in Gossypium hirsutum.BMC genomics · 2025Article
- Homeostasis of DNA Hemi-Methylation in Arabidopsis through Methylation Maintenance, DNA Replication, and Nucleosome Positioning Mechanisms.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Plants repress ROS1 expression to attenuate heat-induced transposon burst.Nature plants · 2025Article
- Comprehensive analysis of MAGE-A10 in pan-cancer and its validation in gastric cancer.Scientific reports · 2025Article
- DNA methylation at retrotransposons protects the germline by preventing NRF1-mediated activation.EMBO reports · 2025Article
84 more citing papers are in PubMed but not listed here.
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Authors and funding
21 authors at 6 institutions in 3 countries.
C Jake HarrisDepartment of Molecular, Cell and Developmental Biology, University of California at Los Angeles, Los Angeles, CA 90095, USA.ORCID 0000-0001-5120-0377
Marion ScheibeQuantitative Proteomics, Institute of Molecular Biology, 55128 Mainz, Germany.ORCID 0000-0002-2181-2214
Somsakul Pop WongpaleeDepartment of Molecular, Cell and Developmental Biology, University of California at Los Angeles, Los Angeles, CA 90095, USA.ORCID 0000-0002-3169-5509
Wanlu LiuDepartment of Molecular, Cell and Developmental Biology, University of California at Los Angeles, Los Angeles, CA 90095, USA.
Evan M CornettCenter for Epigenetics, Van Andel Research Institute, Grand Rapids, MI 49503, USA.ORCID 0000-0003-1468-4506
Robert M VaughanCenter for Epigenetics, Van Andel Research Institute, Grand Rapids, MI 49503, USA.ORCID 0000-0002-3046-4207
Xueqin LiNational Key Laboratory of Plant Molecular Genetics, CAS Center for Excellence in Molecular Plant Sciences, Shanghai Center for Plant Stress Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 201602, China.ORCID 0000-0003-4954-946X
Wei ChenNational Key Laboratory of Plant Molecular Genetics, CAS Center for Excellence in Molecular Plant Sciences, Shanghai Center for Plant Stress Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 201602, China.
Yan XueDepartment of Molecular, Cell and Developmental Biology, University of California at Los Angeles, Los Angeles, CA 90095, USA.ORCID 0000-0003-0871-8853
Zhenhui ZhongDepartment of Molecular, Cell and Developmental Biology, University of California at Los Angeles, Los Angeles, CA 90095, USA.ORCID 0000-0002-8438-0375
Linda YenDepartment of Molecular, Cell and Developmental Biology, University of California at Los Angeles, Los Angeles, CA 90095, USA.
William D BarshopDepartment of Biological Chemistry, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.
Shima RayatpishehDepartment of Biological Chemistry, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.
Javier Gallego-BartolomeDepartment of Molecular, Cell and Developmental Biology, University of California at Los Angeles, Los Angeles, CA 90095, USA.
Martin GrothDepartment of Molecular, Cell and Developmental Biology, University of California at Los Angeles, Los Angeles, CA 90095, USA.
Zonghua WangState Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crops, Fujian Agriculture and Forestry University, 350002 Fuzhou, China.
James A WohlschlegelDepartment of Biological Chemistry, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.ORCID 0000-0003-3399-901X
Jiamu DuNational Key Laboratory of Plant Molecular Genetics, CAS Center for Excellence in Molecular Plant Sciences, Shanghai Center for Plant Stress Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 201602, China.ORCID 0000-0002-1337-0786
Scott B RothbartCenter for Epigenetics, Van Andel Research Institute, Grand Rapids, MI 49503, USA.ORCID 0000-0003-1631-5392
Falk ButterQuantitative Proteomics, Institute of Molecular Biology, 55128 Mainz, Germany. f.butter@imb-mainz.de jacobsen@ucla.edu.ORCID 0000-0002-7197-7279
Steven E JacobsenDepartment of Molecular, Cell and Developmental Biology, University of California at Los Angeles, Los Angeles, CA 90095, USA. f.butter@imb-mainz.de jacobsen@ucla.edu.ORCID 0000-0001-9483-138X
University of California, Los Angeles · USChinese Academy of Sciences · CNVan Andel Institute · USInstitute of Molecular Biology · DEHoward Hughes Medical Institute · USMinjiang University · CN
Funding
UCLA NIGMS T32 Program AssessmentT32GM007185 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI TORRES, JORGE · 1985 to 2020
$21.7MProteolytic Control of Iron Metabolism by the Ubiquitin Ligase FBXL5R01GM089778 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI WOHLSCHLEGEL, JAMES AKIRA · 2010 to 2023
$4.0MGenetics of DNA methylation patterning of arabidopsis.R37GM060398 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI JACOBSEN, STEVEN E · 2009 to 2018
$3.0MMolecular mechanisms of chromatin and epigenetic regulationR35GM124736 · NIGMS · VAN ANDEL RESEARCH INSTITUTE · PI ROTHBART, SCOTT · 2017 to 2021
$2.4MGenetics of DNA Methylation Patterning of ArabidopsisR01GM060398 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI JACOBSEN, STEVEN E · 2000 to 2008
$2.2MHoward Hughes Medical InstituteNIGMS NIH HHS R01 GM060398NIGMS NIH HHS R01 GM089778NIGMS NIH HHS R35 GM124736NIGMS NIH HHS R37 GM060398NIGMS NIH HHS T32 GM007185
Abstract
DNA methylation generally functions as a repressive transcriptional signal, but it is also known to activate gene expression. In either case, the downstream factors remain largely unknown. By using comparative interactomics, we isolated proteins in
Indexed as
DNA MethylationGene Expression Regulation, PlantTranscription, GeneticArabidopsisArabidopsis ProteinsHistone-Lysine N-MethyltransferaseHSP40 Heat-Shock ProteinsMethyltransferasesProtein DomainsArabidopsis ProteinsHistone-Lysine N-MethyltransferaseHSP40 Heat-Shock ProteinsMethyltransferasesSU(VAR)3-9SUVH1 protein, ArabidopsisSUVH3 protein, Arabidopsis
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