Evidence map›Paper›PMID 30523039›Full record

Observational studyCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology2019

The ColoCare Study: A Paradigm of Transdisciplinary Science in Colorectal Cancer Outcomes.

Cornelia M Ulrich, Biljana Gigic, Jürgen Böhm, Jennifer Ose, Richard Viskochil, Martin Schneider, Graham A Colditz, Jane C Figueiredo, William M Grady, Christopher I Li and 4 more

Registry-linked trialAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02328677 (ColoCare Transdisciplinary Research in Colorectal Cancer Prognosis), which is not on this map. Cited by 69 papers.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02328677 recruitingnot on this map

ColoCare Transdisciplinary Research in Colorectal Cancer Prognosis

TypeobservationalSponsorUniversity of UtahRan2007 to 2030Enrolled5,000ConditionsColorectal Cancer
3 · Its place in the literature

Who cites it

69 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Engagement in Cancer Epidemiology Cohorts.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2026
    Article
  5. Observational
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. The Translational Research Program in Cancer Differences across Populations.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2025
    Article
  13. Observational
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Alcohol Consumption and Smoking History at the Time of Diagnosis and the Risk of Colorectal Cancer Recurrence and Mortality: Results from the ColoCare Study.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2025
    Article
  20. Review

9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Cornelia M Ulrich *Huntsman Cancer Institute, Salt Lake City, Utah. neli.ulrich@hci.utah.edu.
Biljana Gigic *Department of General, Visceral and Transplantation Surgery, University Hospital of Heidelberg, Heidelberg, Germany.
Jürgen BöhmHuntsman Cancer Institute, Salt Lake City, Utah.
Jennifer OseHuntsman Cancer Institute, Salt Lake City, Utah.ORCID 0000-0002-2030-9676
Richard ViskochilHuntsman Cancer Institute, Salt Lake City, Utah.
Martin SchneiderDepartment of General, Visceral and Transplantation Surgery, University Hospital of Heidelberg, Heidelberg, Germany.
Graham A Colditz *Division of Public Health Sciences, Department of Surgery, Washington University School of Medicine and Siteman Cancer Center, St. Louis, Missouri.ORCID 0000-0002-7307-0291
Jane C Figueiredo *Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California.
William M Grady *Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington.ORCID 0000-0002-0129-7809
Christopher I Li *Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington.
David Shibata *Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee.
Erin M Siegel *Cancer Epidemiology Program, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida.
Adetunji T Toriola *Division of Public Health Sciences, Department of Surgery, Washington University School of Medicine and Siteman Cancer Center, St. Louis, Missouri.
Alexis Ulrich *Department of General, Visceral and Transplantation Surgery, University Hospital of Heidelberg, Heidelberg, Germany.

Funding

Translational Bioimaging Core Shared ResourceP30CA015704 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Eric Collisson · 1985 to 2026
$296.4M
Washington University Center for Cellular ImagingP30CA091842 · NCI · WASHINGTON UNIVERSITY · PI AIMEE S JAMES · 2001 to 2026
$128.0M
TRANSLATIONAL RESEARCHP30CA076292 · NCI · UNIVERSITY OF SOUTH FLORIDA · PI Christine O'Connell · 1998 to 2026
$93.5M
UTAH REGIONAL CANCER CENTERP30CA042014 · NCI · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI KATHARINE S ULLMAN · 1986 to 2026
$72.6M
Transdisciplinary Team Science in Colorectal Cancer Prognosis: the ColoCare StudyU01CA206110 · NCI · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Jane C. Figueiredo, Christopher I Li · 2016 to 2026
$18.6M
Identify and validate novel epigenetic molecular markers for colorectal neoplasmU01CA152756 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI GRADY, WILLIAM MALLORY, GUDA, KISHORE · 2010 to 2021
$6.7M
Discovery and verification of novel biomarkers of colorectal cancer recurrenceR01CA189184 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI LI, CHRISTOPHER I, ULRICH, CORNELIA M · 2015 to 2020
$5.6M
Metabolomic Strategies for Discovery and Validation of Biomarkers of Colorectal Cancer RecurrenceR01CA207371 · NCI · UNIVERSITY OF UTAH · PI LI, CHRISTOPHER I, ULRICH, CORNELIA M · 2017 to 2022
$3.9M
(PQ6) Radiogenomics of colorectal polyps to assess benign proliferative vs. premalignant states.R01CA220004 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI GRADY, WILLIAM MALLORY, HALBERG, RICHARD BROTT · 2017 to 2021
$3.2M
(PQC1) Accelerated biological aging and colon polyp to cancer progressionR01CA194663 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI GRADY, WILLIAM MALLORY · 2015 to 2018
$1.6M
NCI NIH HHS P30 CA015704NCI NIH HHS P30 CA042014NCI NIH HHS P30 CA076292NCI NIH HHS P30 CA091842NCI NIH HHS R01 CA189184NCI NIH HHS R01 CA194663NCI NIH HHS R01 CA207371NCI NIH HHS R01 CA220004NCI NIH HHS U01 CA152756NCI NIH HHS U01 CA206110
6 · The paper itself

Abstract

backgroundColorectal cancer is a leading cause of cancer death. Biomarkers to predict treatment outcomes are needed, as is evidence whether postdiagnosis diet and lifestyle can affect well-being and clinical outcomes. The international ColoCare Consortium aims to identify new biologic markers (e.g., metabolomic, transcriptomic, metagenomic, genetic, epigenetic, proteomic markers) that predict clinical outcomes, and to characterize associations between modifiable risk factors (e.g., diet, supplement use, physical activity) with short-term and long-term patient-reported and clinical outcomes among patients with colorectal cancer.

conclusionsColoCare is a consortium for the investigation of multilevel factors relevant to colorectal cancer survivorship. IMPACT: The combination of a comprehensive set of biospecimens collected at multiple time points, jointly with detailed assessments of health behaviors and other prognostic factors, results in a unique resource that facilitates wide-ranging, innovative, and impactful research on colorectal cancer.

Indexed as

Quality of LifeAgedBiomarkers, TumorColorectal NeoplasmsCombined Modality TherapyFemaleFollow-Up StudiesGenomicsHumansMaleMetabolomicsMiddle AgedNeoplasm Recurrence, LocalNon-Randomized Controlled Trials as TopicPatient Reported Outcome MeasuresPrognosisBiomarkers, Tumor

Identifiers

PMID30523039
PMCPMC6420345

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.