ArticleJournal of diabetes and its complications2019
The triglyceride to high-density lipoprotein cholesterol (TG/HDL-C) ratio as a predictor of insulin resistance, β-cell function, and diabetes in Hispanics and African Americans.
Article in Journal of diabetes and its complications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers, 1 of them a synthesis that pooled it.
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Who cites it
64 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Hypertriglyceridemia is a dose-dependent risk factor for type 2 diabetes mellitus: a systematic review and meta-analysis.Frontiers in endocrinology · 2025Pooled it
- Ratio That Reveals Risk: Defining TG:HDL-C Ratio Cutoff for Insulin Resistance in Adolescents with Obesity.Children (Basel, Switzerland) · 2026Article
- Early detection and risk stratification of insulin resistance in children and adolescents with excess weight: a sdLDL/oxLDL-Based model.Clinical and experimental medicine · 2026Article
- The Association between Triglycerides to High-density Lipoprotein Cholesterol (TG/HDL-C) Ratio and 10-year Prospective Risk of Type 2 Diabetes Mellitus: Yazd Healthy Heart Project.Advanced biomedical research · 2026Article
- Triglycerides to high-density lipoprotein cholesterol ratio and its association with periodontitis-a systematic review.BDJ open · 2025Article
- Relationship Between Insulin Resistance Indicators and Type 2 Diabetes Mellitus in Romania.International journal of molecular sciences · 2025Article
- Identification of age-specific risk factors for hyperuricemia: a machine learning-driven stratified analysis in health examination cohorts.BMC medical informatics and decision making · 2025Article
- Association of the remnant cholesterol to high-density lipoprotein cholesterol ratio with mortality in peritoneal dialysis patients.Lipids in health and disease · 2025Article
- Association Between Nontraditional Lipid Profiles and the Risk of Type 2 Diabetes Mellitus in Chinese Adults With Hypertension: Findings From the China Hypertension Registry Study.Journal of clinical hypertension (Greenwich, Conn.) · 2025Article
- Association of triglycerides/high-density lipoprotein ratio with cardiometabolic risk factors in children from mothers who had gestational diabetes.Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo · 2025Article
- Association between the triglyceride to high-density lipoprotein cholesterol ratio and type 2 diabetes mellitus in non-alcoholic fatty liver disease.Scientific reports · 2024Article
- BMI trajectories from birth to young adulthood associate with distinct cardiometabolic profiles.BMC medicine · 2024Article
- Triglyceride and Glucose Index as an Optimal Predictor of Metabolic Syndrome in Lebanese Adults.Nutrients · 2024Article
- Association between four insulin resistance surrogates and the risk of esophageal cancer: a prospective cohort study using the UK Biobank.Journal of cancer research and clinical oncology · 2024Article
- Prognostic Value of High-Density Lipoprotein Cholesterol in Patients with Overt Hepatic Encephalopathy.Biomedicines · 2024Article
- The Triglyceride/HDL Ratio as a Surrogate Biomarker for Insulin Resistance.Biomedicines · 2024Review
- The association between non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio with type 2 diabetes mellitus: recent findings from NHANES 2007-2018.Lipids in health and disease · 2024Article
- Higher LDL-C/HDL-C Ratio Is Associated with Elevated HbA1c and Decreased eGFR Levels and Cardiac Remodeling in Elderly with Hypercholesterolemia.Journal of cardiovascular development and disease · 2024Article
- Association of remnant cholesterol and newly diagnosed early-onset type 2 diabetes mellitus in Chinese population: A retrospective cross-sectional study.Journal of diabetes · 2024Article
- Comprehensive genetic study of the insulin resistance marker TG:HDL-C in the UK Biobank.Nature genetics · 2024Article
4 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
objectiveThe TG/HDL-C ratio is used as a marker of insulin resistance (IR) in Caucasians; however, there is limited data in other ethnic groups. We hypothesized that the TG/HDL-C ratio is associated with IR in Hispanics and African Americans (AA). RESEARCH DESIGN AND
methodsData from the Insulin Resistance Atherosclerosis Family Study was examined for associations between TG/HDL-C ratio and IR, β-cell function and incident diabetes in non-diabetic Hispanics (n = 872, 63% female) and AA (n = 371, 61% female). Insulin sensitivity index (S
resultsHigher TG/HDL-C ratio was associated with IR in Hispanic and AA men and women (P < 0.0002), as well as β-cell function in Hispanic women and AA men and women (P < 0.02). TG/HDL-C predicted incident type 2 diabetes in women (area under the curves 0.703 and 0.795 for Hispanics and AA respectively).
conclusionsSimilar to Caucasians, the TG/HDL-C ratio can be used to identify IR in Hispanics and AA, and may predict type 2 diabetes in women.
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