Evidence map›Paper›PMID 30522456›Full record

ArticleBMC cancer2018

OMCD: OncomiR Cancer Database.

Aaron L Sarver, Anne E Sarver, Ce Yuan, Subbaya Subramanian

Open access · goldAbstract read
In one paragraph

Article in BMC cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 63 citations in OpenAlex.

  1. Trial
  2. Article
  3. Upregulation ofTranslational andrology and urology · 2026
    Article
  4. Article
  5. Cancer pharmacoinformatics: Databases and analytical tools.Functional & integrative genomics · 2024
    Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. The RNA world: from experimental laboratory to "in silico" approach. Part 1: User friendly RNA expression databases portals.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2024
    Review
  12. Review
  13. Integrative Analysis of the Role ofCurrent issues in molecular biology · 2023
    Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Aaron L SarverInstitute of Health Informatics, University of Minnesota, Minneapolis, MN, USA. sarver@umn.edu.
Anne E SarverDepartment of Surgery, University of Minnesota, 11-212 Moos Tower Mayo Mail Code 195 420 Delaware Street SE, Minneapolis, MN, 55455, USA.
Ce YuanDepartment of Surgery, University of Minnesota, 11-212 Moos Tower Mayo Mail Code 195 420 Delaware Street SE, Minneapolis, MN, 55455, USA.
Subbaya SubramanianDepartment of Surgery, University of Minnesota, 11-212 Moos Tower Mayo Mail Code 195 420 Delaware Street SE, Minneapolis, MN, 55455, USA. subree@umn.edu.ORCID http://orcid.org/0000-0002-2544-480X
University of Minnesota · US

Funding

Translational Pediatric Cancer Epidemiology Research Training GrantT32CA099936 · NCI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI Logan G. Spector · 2004 to 2026
$5.1M
Bioinformatics approaches to solve the "Missing Driver" problem in solid tumorsR50CA211249 · NCI · UNIVERSITY OF MINNESOTA · PI SARVER, AARON L · 2016 to 2020
$565k
Atypical Chemokine Receptor 4 (ACKR4) in Anti-tumor Immunity in colorectal cancerR03CA219129 · NCI · UNIVERSITY OF MINNESOTA · PI SUBRAMANIAN, SUBBAYA · 2017 to 2018
$147k
Masonic Cancer Center, University of Minnesota Norman Wells Memorial Colorectal Cancer FellowshipNCI NIH HHS R03CA219129NCI NIH HHS R50 CA211249NCI NIH HHS T32 CA099936University of Minnesota Healthy Foods Healthy Lives Institute Graduate and Professional Student Research Grant
6 · The paper itself

Abstract

backgroundmicroRNAs (miRNAs) are crucially important in the development of cancer. Their dysregulation, commonly observed in various types of cancer, is largely cancer-dependent. Thus, to understand the tumor biology and to develop accurate and sensitive biomarkers, we need to understand pan-cancer miRNA expression. CONSTRUCTIONS: At the University of Minnesota, we developed the OncomiR Cancer Database (OMCD), hosted on a web server, which allows easy and systematic comparative genomic analyses of miRNA sequencing data derived from more than 9500 cancer patients tissue samples available in the Cancer Genome Atlas (TCGA). OMCD includes associated clinical information and is searchable by organ-specific terms common to the TCGA.

conclusionsFreely available to all users ( www.oncomir.umn.edu/omcd/ ), OMCD enables (1) simple visualization of TCGA miRNA sequencing data, (2) statistical analysis of differentially expressed miRNAs for each cancer type, and (3) exploration of miRNA clusters across cancer types. DATABASE URL: www.oncomir.umn.edu/omcd.

Indexed as

Databases, GeneticDatasets as TopicGene Expression ProfilingGene Expression Regulation, NeoplasticHumansMicroRNAsNeoplasmsRNA, MessengerMicroRNAsRNA, MessengerCancerDatabasemicroRNAmiRNAmiRNA expression profileOncomiRTCGA

Identifiers

PMID30522456
PMCPMC6282392
OpenAlexW2952539953

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.