Evidence map›Paper›PMID 30522446›Full record

ArticleBMC infectious diseases2018

Is Toxoplasma gondii infection correlated with nonalcoholic fatty liver disease?- a population-based study.

Jiaofeng Huang, Haoyang Zhang, Shiying Liu, Mingfang Wang, Bo Wan, Bharat Velani, Yueyong Zhu, Su Lin

Open access · goldAbstract read
In one paragraph

Article in BMC infectious diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. The Association ofMedical sciences (Basel, Switzerland) · 2023
    Article
  5. Article
  6. Article
  7. The Association ofInternational journal of environmental research and public health · 2022
    Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Seroprevalence ofIranian journal of parasitology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Jiaofeng HuangDepartment of Liver Research Center, the First Affiliated Hospital of Fujian Medical University, Fuzhou, No. 20, Chazhong Road, Taijiang District, Fuzhou, 350001, Fujian, China.
Haoyang ZhangSchool of Public Health, Sun Yat-sen University, Guangzhou, 350002, Guangdong, China.
Shiying LiuDepartment of Liver Research Center, the First Affiliated Hospital of Fujian Medical University, Fuzhou, No. 20, Chazhong Road, Taijiang District, Fuzhou, 350001, Fujian, China.
Mingfang WangDepartment of Liver Research Center, the First Affiliated Hospital of Fujian Medical University, Fuzhou, No. 20, Chazhong Road, Taijiang District, Fuzhou, 350001, Fujian, China.
Bo WanFaculty of Life Sciences and Medicine, King's College London, London, SE1 1UL, UK.
Bharat VelaniBasildon and Thurrock University Hospitals NHS Foundation Trust, Nethermayne, Basildon, Essex, SS16 5NL, UK.
Yueyong ZhuDepartment of Liver Research Center, the First Affiliated Hospital of Fujian Medical University, Fuzhou, No. 20, Chazhong Road, Taijiang District, Fuzhou, 350001, Fujian, China.
Su LinDepartment of Liver Research Center, the First Affiliated Hospital of Fujian Medical University, Fuzhou, No. 20, Chazhong Road, Taijiang District, Fuzhou, 350001, Fujian, China. sumer5129@fjmu.edu.cn.ORCID http://orcid.org/0000-0001-7517-9859
Fujian Medical University · CNBasildon and Thurrock University Hospitals NHS Foundation Trust · GBKing's College London · GBSun Yat-sen University · CN

Funding

Fujian Provincial Department of Science and Technology (CN) 2016-CX-33the Natural Science Foundation of Fujian Province the Pilot of Fujian Science and Technology Project 2016Y0040the Natural Science Foundation of Fujian Province the Pilot of Fujian Science and Technology Project 2017J01187
6 · The paper itself

Abstract

backgroundPrevious studies have suggested that Toxoplasma gondii (T. gondii) infection might be associated with fatty liver disease. However, the relationship between non-alcoholic fatty liver disease (NAFLD) and T. gondii infection has not been investigated in a large population. We aimed to study the relationship between those two diseases using a population-based dataset from the United States.

methodsThe data were collected from the third National Health and Nutrition Examination Survey (NHANES III) between 1988 and 1994. Statistical analysis was applied to compare the prevalence of NAFLD in anti-T. gondii antibody-positive participants with antibody-negative ones.

resultsA total of 9465 persons with a mean age of 44.33 ± 16.21 years, 46.9% of which were males, were included in the final analysis. Their mean BMI was 27.60 ± 5.96 kg/m

conclusionsPatients with T. gondii infection may have a higher prevalence of NAFLD. Age may have an effect on the increase of NAFLD in the T. gondii seropositive population.

Indexed as

Non-alcoholic Fatty Liver DiseaseToxoplasmosisAdultCross-Sectional StudiesFemaleHumansMaleMiddle AgedUnited StatesNHANESNon-alcoholic fatty liverToxoplasma gondii

Identifiers

PMID30522446
PMCPMC6282358
OpenAlexW2902008211

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.