Trial reportAmerican journal of respiratory and critical care medicine2019
Oral Vitamin C (500 mg/d) to Pregnant Smokers Improves Infant Airway Function at 3 Months (VCSIP). A Randomized Trial.
Registry-linked trialOpen access · greenAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph
Trial report in American journal of respiratory and critical care medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06106646 (Assessing the Effect of Vitamin C on Infant Lung Function When Given to Pregnant Women Who Smoke -), which is not on this map. Cited by 35 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 7% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Assessing the Effect of Vitamin C on Infant Lung Function When Given to Pregnant Women Who Smoke - (Long Term Follow-up of a Randomized Trial)
Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.
- A meta-analysis of the effects of vitamin C supplementation for pregnant smokers on the pulmonary function of their offspring.BMC pregnancy and childbirth · 2024Pooled it
- Extended Continuous Positive Airway Pressure in Preterm Infants Increases Lung Growth at 6 Months: A Randomized Controlled Trial.American journal of respiratory and critical care medicine · 2025Trial
- Spirometry Versus Forced Oscillation to Assess Lung Function Outcome at 5 Years of Age.Pediatric pulmonology · 2025Trial
- Vitamin C supplementation improves placental function and alters placental gene expression in smokers.Scientific reports · 2024Trial
- Development and Validation of a Novel Placental DNA Methylation Biomarker of Maternal Smoking during Pregnancy in the ECHO Program.Environmental health perspectives · 2024Trial
- Maternal and perinatal nutritional programming of lung health and disease in childhood and early adulthood: Research gaps and opportunities-National Heart, Lung, and Blood Institute/National Institutes of Health Workshop Report.The Journal of allergy and clinical immunology · 2026Article
- Maternal environmental exposure and early-life health risks: The modulating role of nutritional status-A scoping review.iScience · 2026Review
- Pulmonary function tests in the neonatal intensive care unit and beyond: a clinical review.Journal of perinatology : official journal of the California Perinatal Association · 2026Review
- Daily intake of antioxidants ameliorates PMFrontiers in nutrition · 2026Article
- Antenatal Vitamin C differentially affects lung development in normally grown and growth restricted sheep.Pediatric research · 2025Article
- Is there a role for vitamin supplementation in pollutant-related childhood asthma?The Journal of allergy and clinical immunology · 2025Article
- Impact of E-Cigarettes on Fetal and Neonatal Lung Development: The Influence of Oxidative Stress and Inflammation.Antioxidants (Basel, Switzerland) · 2025Review
- Temporal Dynamics of Oxidative Stress and Inflammation in Bronchopulmonary Dysplasia.International journal of molecular sciences · 2024Review
- Defining and Promoting Pediatric Pulmonary Health: Assessing Lung Function and Structure.Pediatrics · 2023Article
- Nutrient Supplementation during the Prenatal Period in Substance-Using Mothers: A Narrative Review of the Effects on Offspring Development.Nutrients · 2023Review
- The Role of Vitamins in the Pathogenesis of Asthma.International journal of molecular sciences · 2023Review
- The Role of Lung Function in Determining Which Children Develop Asthma.The journal of allergy and clinical immunology. In practice · 2023Article
- Perspectives: on Precision Nutrition Research in Heart, Lung, and Blood Diseases and Sleep Disorders.Advances in nutrition (Bethesda, Md.) · 2022Article
- The Variable Nature of Vitamin C-Does It Help When Dealing with Coronavirus?Antioxidants (Basel, Switzerland) · 2022Review
- Review
Corrections and comments
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Authors and funding
21 authors at 8 institutions in 2 countries.
Cindy T McEvoy1 Department of Pediatrics.ORCID 0000-0001-8501-8813
Lyndsey E Shorey-Kendrick2 Division of Neuroscience, Oregon National Primate Research Center, Beaverton, Oregon.
Kristin Milner1 Department of Pediatrics.
Diane Schilling1 Department of Pediatrics.
Christina Tiller3 Department of Pediatrics and.
Brittany Vuylsteke1 Department of Pediatrics.
Ashley Scherman1 Department of Pediatrics.
Keith Jackson4 PeaceHealth Southwest Medical Center, Vancouver, Washington.
David M Haas5 Department of Obstetrics and Gynecology, Indiana University School of Medicine, Indianapolis, Indiana.
Julia Harris1 Department of Pediatrics.
Robert Schuff6 Department of Medical Informatics and Clinical Epidemiology.
Byung S Park8 Oregon Health & Science University-Portland State University School of Public Health and Knight Cancer Institute, Portland, Oregon; and.
Annette Vu6 Department of Medical Informatics and Clinical Epidemiology.
Dale F Kraemer6 Department of Medical Informatics and Clinical Epidemiology.
Julie Mitchell7 Oregon Clinical & Translational Research Institute, and.
Jill Metz6 Department of Medical Informatics and Clinical Epidemiology.
David Gonzales9 Division of Pulmonary & Critical Care Medicine, Oregon Health & Science University, Portland, Oregon.
Carol Bunten10 Vancouver Clinic, Vancouver, Washington.
Eliot R Spindel2 Division of Neuroscience, Oregon National Primate Research Center, Beaverton, Oregon.
Robert S Tepper3 Department of Pediatrics and.
Cynthia D Morris6 Department of Medical Informatics and Clinical Epidemiology.
Pediatrics and Genetics · USInstitute for Medical Informatics and Biostatistics · CHOregon National Primate Research Center · USIndiana University School of MedicineOregon Health & Science University · USPortland State University · USSouthwest Washington Medical Center · USVancouver Clinic · US
Funding
Upgrade of confocal microscopy at the Oregon National Primate Research CenterP51OD011092 · OD · OREGON HEALTH & SCIENCE UNIVERSITY · PI Bonnie J. Nagel · 2012 to 2026
$203.9MOregon Clinical and Translational Research Institute - The National COVID Cohort Collaborative (N3C)UL1TR002369 · NCATS · OREGON HEALTH & SCIENCE UNIVERSITY · PI Cynthia D Morris, Christopher G. Slatore · 2017 to 2026
$78.4MOregon Clinical and Translational Research InstituteUL1TR000128 · NCATS · OREGON HEALTH & SCIENCE UNIVERSITY · PI ELLISON, DAVID H · 2012 to 2015
$28.7MMaternal vitamin C supplementation to decrease effects of smoking during pregnancy on infant lung function and health:Follow-up of 2 randomized trials and association with changes in DNA methylationUH3OD023288 · OD · OREGON HEALTH & SCIENCE UNIVERSITY · PI Cynthia T McEvoy, ELIOT R SPINDEL · 2018 to 2026
$12.1MVitC to Decrease Effects of Smoking in Pregnancy on Infant Lung Function-CCC-LeadR01HL105447 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI MCEVOY, CYNTHIA T · 2012 to 2021
$9.8MMaternal vitamin C supplementation to decrease effects of smoking during pregnancy on infant lung function and health:Follow-up of 2 randomized trials and association with changes in DNA methylationUG3OD023288 · OD · OREGON HEALTH & SCIENCE UNIVERSITY · PI MCEVOY, CYNTHIA T, SPINDEL, ELIOT R · 2016 to 2024
$4.7MVitC to Decrease Effects of Smoking in Pregnancy on Infant Lung Function-DCCR01HL105460 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI MORRIS, CYNTHIA D · 2012 to 2021
$2.4MNCATS NIH HHS UL1 TR000128NCATS NIH HHS UL1 TR002369NHLBI NIH HHS R01 HL105447NHLBI NIH HHS R01 HL105460NIH HHS P51 OD011092NIH HHS UG3 OD023288NIH HHS UH3 OD023288
Abstract
PubMed holds no abstract for this paper.
Indexed as
Administration, OralAdultAscorbic AcidDietary SupplementsDouble-Blind MethodFemaleForced Expiratory Flow RatesHumansInfantPregnancyPregnancy ComplicationsPrenatal Exposure Delayed EffectsSmokingAscorbic Acidforced expiratory flowsinfant pulmonary functionsmoking in pregnancyvitamin Cwheezing
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
NCT06106646ClinicalTrials.gov
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.