Evidence map›Paper›PMID 30521871›Full record

ArticleBiochimica et biophysica acta. Molecular cell research2019

5-Azido-8-ethynyl-NAADP: A bifunctional, clickable photoaffinity probe for the identification of NAADP receptors.

Gihan S Gunaratne, Peiling Su, Jonathan S Marchant, James T Slama, Timothy F Walseth

Open access · greenAbstract read
In one paragraph

Article in Biochimica et biophysica acta. Molecular cell research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. NAADP-Mediated CaHandbook of experimental pharmacology · 2023
    Article
  4. NAADP-Dependent TPC Current.Handbook of experimental pharmacology · 2023
    Article
  5. NAADP-Evoked CaHandbook of experimental pharmacology · 2023
    Article
  6. Article
  7. NAADP-binding proteins find their identity.Trends in biochemical sciences · 2022
    Review
  8. Article
  9. Article
  10. NAADP: From Discovery to Mechanism.Frontiers in immunology · 2021
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Gihan S GunaratneDepartment of Pharmacology, University of Minnesota Medical School, 312 Church St., Minneapolis, MN 55455-0217, United States of America.
Peiling SuDepartment of Medicinal and Biological Chemistry, University of Toledo College of Pharmacy and Pharmaceutical Sciences, 3000 Arlington Avenue, Toledo, OH 43614, United States of America.
Jonathan S MarchantDepartment of Cell Biology, Neurobiology & Anatomy, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226-0509, United States of America.
James T SlamaDepartment of Medicinal and Biological Chemistry, University of Toledo College of Pharmacy and Pharmaceutical Sciences, 3000 Arlington Avenue, Toledo, OH 43614, United States of America.
Timothy F WalsethDepartment of Pharmacology, University of Minnesota Medical School, 312 Church St., Minneapolis, MN 55455-0217, United States of America. Electronic address: walse001@umn.edu.
University of Minnesota · USUniversity of Toledo · USMedical College of Wisconsin · US

Funding

Functional architecture of IP3-evoked local Ca2+ signalsR01GM088790 · NIGMS · UNIVERSITY OF MINNESOTA · PI MARCHANT, JONATHAN S, SLAMA, JAMES T · 2009 to 2025
$4.7M
Identification of the Elusive NAADP ReceptorR15GM131329 · NIGMS · UNIVERSITY OF TOLEDO HEALTH SCI CAMPUS · PI SLAMA, JAMES T · 2018 to 2018
$462k
Chemobiologic Approach to NAADP SignalingR15GM100444 · NIGMS · UNIVERSITY OF TOLEDO HEALTH SCI CAMPUS · PI SLAMA, JAMES T · 2012 to 2012
$351k
NIGMS NIH HHS R01 GM088790NIGMS NIH HHS R15 GM100444NIGMS NIH HHS R15 GM131329
6 · The paper itself

Abstract

Nicotinic acid adenine dinucleotide phosphate is an evolutionarily conserved second messenger, which mobilizes Ca

Indexed as

Calcium SignalingFluorescent DyesStaining and LabelingUltraviolet RaysAnimalsCell Line, TumorHumansNADPSea UrchinsFluorescent DyesNAADPNADPClickable NAADP analogIntracellular calcium releaseNicotinic acid adenine dinucleotide phosphate (NAADP)Nucleotide analogsPhotoaffinity labeling

Identifiers

PMID30521871
PMCPMC8101546
OpenAlexW2902687195

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.