Evidence map›Paper›PMID 30521761›Full record

ArticleAmerican journal of respiratory and critical care medicine2019

Pharmacotherapy of Obstructive Sleep Apnea: Is Salvation Just Around a Corner?

Thomaz Fleury Curado, Slava Berger, Vsevolod Y Polotsky

Abstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of respiratory and critical care medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. The Global Burden of Obstructive Sleep Apnea.Diagnostics (Basel, Switzerland) · 2025
    Review
  2. Article
  3. Obstructive sleep apnea.Handbook of clinical neurology · 2022
    Review
  4. Article
  5. Update in Sleep 2019.American journal of respiratory and critical care medicine · 2020
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Thomaz Fleury Curado1 Johns Hopkins University School of Medicine Baltimore, Maryland.
Slava Berger1 Johns Hopkins University School of Medicine Baltimore, Maryland.
Vsevolod Y Polotsky1 Johns Hopkins University School of Medicine Baltimore, Maryland.

Funding

Melanocortin 4 signaling in the carotid body in obesityR01HL133100 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI Vsevolod Y Polotsky, Wan-yee Tang · 2016 to 2026
$7.1M
Treatment of Sleep Apnea by Targeting Leptin SignalingR01HL128970 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI MENDELOWITZ, DAVID, POLOTSKY, VSEVOLOD Y · 2015 to 2023
$5.4M
Chemogenetic approach to treat Obstructive Sleep ApneaR01HL138932 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI POLOTSKY, VSEVOLOD Y · 2017 to 2020
$2.4M
NHLBI NIH HHS R01 HL128970NHLBI NIH HHS R01 HL133100NHLBI NIH HHS R01 HL138932
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Sleep Apnea, ObstructiveAtomoxetine HydrochlorideCross-Over StudiesDouble-Blind MethodHumansMandelic AcidsAtomoxetine HydrochlorideMandelic Acidsoxybutynin

Identifiers

PMID30521761
PMCPMC6519854

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.