Evidence map›Paper›PMID 30521755›Full record

ArticleAnalytical chemistry2019

Quantitative Detection of Fipronil and Fipronil-Sulfone in Sera of Black-Tailed Prairie Dogs and Rats after Oral Exposure to Fipronil by Camel Single-Domain Antibody-Based Immunoassays.

Kai Wang, Natalia Vasylieva, Debin Wan, David A Eads, Jun Yang, Tyler Tretten, Bogdan Barnych, Ji Li, Qing X Li, Shirley J Gee and 2 more

Abstract read
In one paragraph

Article in Analytical chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Kai WangBeijing Advanced Innovation Center for Food Nutrition and Human Health, College of Resources and Environmental Sciences , China Agricultural University , Beijing 100193 , China.
Natalia VasylievaDepartment of Entomology and UCD Comprehensive Cancer Center , University of California , Davis , California 95616 , United States.
Debin WanDepartment of Entomology and UCD Comprehensive Cancer Center , University of California , Davis , California 95616 , United States.
David A EadsDepartment of Biology , Colorado State University , Fort Collins , Colorado 80523 , United States.
Jun YangDepartment of Entomology and UCD Comprehensive Cancer Center , University of California , Davis , California 95616 , United States.
Tyler TrettenU.S. Fish and Wildlife Service , Black-Footed Ferret Conservation Center , Carr , Colorado 80612 , United States.
Bogdan BarnychDepartment of Entomology and UCD Comprehensive Cancer Center , University of California , Davis , California 95616 , United States.
Ji LiBeijing Advanced Innovation Center for Food Nutrition and Human Health, College of Resources and Environmental Sciences , China Agricultural University , Beijing 100193 , China.
Qing X LiDepartment of Molecular Biosciences and Bioengineering , University of Hawaii at Manoa , 1955 East-West Road , Honolulu , Hawaii 96822 , United States.ORCID 0000-0003-4589-2869
Shirley J GeeDepartment of Entomology and UCD Comprehensive Cancer Center , University of California , Davis , California 95616 , United States.
Bruce D HammockDepartment of Entomology and UCD Comprehensive Cancer Center , University of California , Davis , California 95616 , United States.ORCID 0000-0003-1408-8317
Ting XuBeijing Advanced Innovation Center for Food Nutrition and Human Health, College of Resources and Environmental Sciences , China Agricultural University , Beijing 100193 , China.ORCID 0000-0002-6843-5663

Funding

Workshop on Environmental Technology Transfer and EntrepreneurshipP42ES004699 · NIEHS · UNIVERSITY OF CALIFORNIA DAVIS · PI HAMMOCK, BRUCE D · 1987 to 2021
$50.1M
NIEHS NIH HHS P42 ES004699
6 · The paper itself

Abstract

The insecticide fipronil can be metabolized to its sulfone in mammalian species. Two camel single-domain antibodies (VHHs) F1 and F6, selective to fipronil and fipronil-sulfone, respectively, were generated and used to develop enzyme linked immunosorbent assays (ELISAs) for the detection of the two compounds in the sera of black-tailed prairie dogs and rats. The limits of detection of fipronil and fipronil-sulfone in the rodent sera by the corresponding ELISAs were 10 and 30 ng mL

Indexed as

Administration, OralAnimalsEnzyme-Linked Immunosorbent AssayImmunizationInsecticidesPyrazolesRatsSciuridaeSingle-Domain Antibodiesfipronilfipronil sulfoneInsecticidesPyrazolesSingle-Domain Antibodies

Identifiers

PMID30521755
PMCPMC7144541

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.