Evidence map›Paper›PMID 30521534›Full record

Trial reportPloS one2018

Molecular epidemiology of HIV-1 infection among men who have sex with men in Taiwan from 2013 to 2015.

Wei-You Li, Marcelo Chen, Szu-Wei Huang, I-An Jen, Sheng-Fan Wang, Jyh-Yuan Yang, Yen-Hsu Chen, Yi-Ming Arthur Chen

Abstract readClinical TrialMulticenter Study
In one paragraph

Trial report in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wei-You LiCenter for Infectious Disease and Cancer Research, Kaohsiung Medical University, Kaohsiung, Taiwan.
Marcelo ChenCenter for Infectious Disease and Cancer Research, Kaohsiung Medical University, Kaohsiung, Taiwan.
Szu-Wei HuangCenter for Infectious Disease and Cancer Research, Kaohsiung Medical University, Kaohsiung, Taiwan.
I-An JenCenter for Infectious Disease and Cancer Research, Kaohsiung Medical University, Kaohsiung, Taiwan.
Sheng-Fan WangCenter for Infectious Disease and Cancer Research, Kaohsiung Medical University, Kaohsiung, Taiwan.
Jyh-Yuan YangResearch and Diagnostic Center, Taipei, Centers for Disease Control, Department of Health, Taipei, Taiwan.
Yen-Hsu ChenCenter for Infectious Disease and Cancer Research, Kaohsiung Medical University, Kaohsiung, Taiwan.
Yi-Ming Arthur ChenCenter for Infectious Disease and Cancer Research, Kaohsiung Medical University, Kaohsiung, Taiwan.ORCID 0000-0002-6068-4964

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Men who have sex with men (MSM) is the major risk population of HIV-1 infection in Taiwan, and its surveillance has become critical in HIV-1 prevention. We recruited MSM subjects from 17 high-risk venues and 4 community centers in northern and southern Taiwan for anonymous HIV-1 screening during 2013-2015. Blood samples were obtained for genotyping and phylogenetic analysis, and a questionnaire survey covering demographic variables and social behavior was conducted. In total, 4,675 subjects were enrolled, yielding a HIV-1 prevalence rate of 4.3% (201/4675). Eight risk factors including subjects who did not always use condoms (OR = 1.509, p = 0.0123), those who used oil-based lubricants (OR = 1.413, p = 0.0409), and those who used recreational drugs (OR = 2.182, p = < .0001) had a higher risk of HIV-1 infection. The annual prevalence and incidence of HIV-1 showed a downward trend from 2013 to 2015 (6.56%, 5.97 per 100 person-years in 2013; 4.53%, 3.97 per 100 person-years in 2014; 1.84%, 2.08 per 100 person-years in 2015). Factors such as always using condoms, water-based lubricant use, correct knowledge of lubricating substitutes, and recreational drug use were significantly associated with the trend of incidence. Phylogenetic tree analysis showed that the cross-regional and international interaction of the local MSM population may have facilitated transmission of HIV. This survey of high-risk venues showed decreased prevalence and incidence of HIV-1 infection in Taiwan from 2013 to 2015, and this may be related to changes in behavioral patterns. Moreover, cross-regional interaction and recreational drug use need to be considered in future surveillance.

Indexed as

HIV InfectionsPhylogenySexual and Gender MinoritiesAdolescentAdultHIV-1HumansIncidenceMaleMiddle AgedMolecular EpidemiologyPrevalenceTaiwan

Identifiers

PMID30521534
PMCPMC6283607

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.