Evidence map›Paper›PMID 30521410›Full record

ArticleIslets2018

In vivo monitoring of intracellular Ca

Reka Lorincz, Christopher H Emfinger, Andrea Walcher, Michael Giolai, Claudia Krautgasser, Maria S Remedi, Colin G Nichols, Dirk Meyer

Open access · hybridAbstract read
In one paragraph

Article in Islets, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Functional analysis of islet cells in vitro, in situ, and in vivo.Seminars in cell & developmental biology · 2020
    Review
  9. Leader β-cells coordinate CaNature metabolism · 2019
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Reka Lorincza Institute of Molecular Biology/CMBI , University of Innsbruck , Innsbruck , Austria.ORCID 0000-0002-9077-3300
Christopher H Emfingerb Department of Cell Biology and Physiology , Washington University School of Medicine , St. Louis , MO , USA.ORCID 0000-0002-9130-4194
Andrea Walchera Institute of Molecular Biology/CMBI , University of Innsbruck , Innsbruck , Austria.ORCID 0000-0001-6624-4284
Michael Giolaia Institute of Molecular Biology/CMBI , University of Innsbruck , Innsbruck , Austria.ORCID 0000-0003-4166-8202
Claudia Krautgassera Institute of Molecular Biology/CMBI , University of Innsbruck , Innsbruck , Austria.
Maria S Remedib Department of Cell Biology and Physiology , Washington University School of Medicine , St. Louis , MO , USA.ORCID 0000-0003-2048-472X
Colin G Nicholsb Department of Cell Biology and Physiology , Washington University School of Medicine , St. Louis , MO , USA.ORCID 0000-0002-4929-2134
Dirk Meyera Institute of Molecular Biology/CMBI , University of Innsbruck , Innsbruck , Austria.ORCID 0000-0002-4020-4484
Universität Innsbruck · ATWashington University in St. Louis · US

Funding

WU P&FP30DK020579 · NIDDK · WASHINGTON UNIVERSITY · PI Jennifer Lynn Powers Carson · 2013 to 2026
$27.1M
ELECTRICAL CONTROL OF INSULIN SECRETIONR01DK109407 · NIDDK · WASHINGTON UNIVERSITY · PI NICHOLS, COLIN G · 2016 to 2019
$1.4M
NIDDK NIH HHS R01 DK109407
6 · The paper itself

Abstract

Assessing the response of pancreatic islet cells to glucose stimulation is important for understanding β-cell function. Zebrafish are a promising model for studies of metabolism in general, including stimulus-secretion coupling in the pancreas. We used transgenic zebrafish embryos expressing a genetically-encoded Ca

Indexed as

AnimalsAnimals, Genetically ModifiedCalciumCalcium Channels, L-TypeEmbryo, NonmammalianInsulin-Secreting CellsZebrafishCalciumCalcium Channels, L-TypeL-type calcium channel alpha(1C)cacna1cCav1.2 channelearly zebrafish developmentGCaMP6sglucose-sensing of beta cellsin vivo imaging

Identifiers

PMID30521410
PMCPMC6300091
OpenAlexW2905041364

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.