Evidence map›Paper›PMID 30520735›Full record

ArticleeLife2018

DNA translocation mechanism of an XPD family helicase.

Kaiying Cheng, Dale B Wigley

Open access · goldAbstract read
In one paragraph

Article in eLife, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 62 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. FeSBCP analogue from cyanobacteria: insights from in vitro and in silico studies.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2025
    Article
  7. Article
  8. International journal of molecular sciences · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Structure, function and evolution of the bacterial DinG-like proteins.Computational and structural biotechnology journal · 2025
    Review
  15. The Role of SF1 and SF2 Helicases in Biotechnological Applications.Applied biochemistry and biotechnology · 2024
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Single-stranded DNA binding protein hitches a ride with thebioRxiv : the preprint server for biology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Kaiying ChengSection of Structural Biology, Department of Medicine, Imperial College London, London, United Kingdom.
Dale B WigleySection of Structural Biology, Department of Medicine, Imperial College London, London, United Kingdom.ORCID http://orcid.org/0000-0002-0786-6726
Imperial College London · GB

Funding

Cancer Research UKMedical Research Council MR/N009258/1Wellcome Trust
6 · The paper itself

Abstract

The XPD family of helicases, that includes human disease-related FANCJ, DDX11 and RTEL1, are Superfamily two helicases that contain an iron-sulphur cluster domain, translocate on ssDNA in a 5'-3' direction and play important roles in genome stability. Consequently, mutations in several of these family members in eukaryotes cause human diseases. Family members in bacteria, such as the DinG helicase from

Indexed as

Adenosine TriphosphateCrystallography, X-RayDEAD-box RNA HelicasesDNA-Binding ProteinsDNA HelicasesDNA RepairDNA, Single-StrandedEscherichia coliEscherichia coli ProteinsFanconi Anemia Complementation Group ProteinsHumansIron-Sulfur ProteinsRNA HelicasesAdenosine TriphosphateBRIP1 protein, humanDDX11 protein, humanDEAD-box RNA HelicasesdinG protein, E coliDNA-Binding ProteinsDNA HelicasesDNA, Single-StrandedEscherichia coli ProteinsFanconi Anemia Complementation Group ProteinsIron-Sulfur ProteinsRNA HelicasesRTEL1 protein, humanDinGDNA repairE. colimolecular biophysicsstructural biologyXPD

Identifiers

PMID30520735
PMCPMC6300356
OpenAlexW2904692440

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.