ArticleJournal of biomedical optics2018
In vivo characterization of connective tissue remodeling using infrared photoacoustic spectra.
Article in Journal of biomedical optics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
11 citing papers in PubMed.
- Spectroscopic photoacoustic imaging of cervical tissue composition in excised human samples.PloS one · 2021Trial
- From lab design to clinical translation: photoacoustic endoscopy.Photoacoustics · 2026Review
- Multi-parametric quantitative evaluation of murine cervical remodeling during pregnancy and postpartum.Scientific reports · 2025Article
- Non-invasive evaluation of endometrial microvessels via in vivo intrauterine photoacoustic endoscopy.Photoacoustics · 2024Article
- Niche preclinical and clinical applications of photoacoustic imaging with endogenous contrast.Photoacoustics · 2023Review
- Miniature side-view dual axes confocal endomicroscope for repetitive in vivo imaging.Biomedical optics express · 2023Article
- Bioengineering and the cervix: The past, current, and future for addressing preterm birth.Current research in physiology · 2023Review
- A multidisciplinary Prematurity Research Cohort Study.PloS one · 2022Article
- Shortwave-infrared meso-patterned imaging enables label-free mapping of tissue water and lipid content.Nature communications · 2020Article
- Evolving cervical imaging technologies to predict preterm birth.Seminars in immunopathology · 2020Review
- Photoacoustic imaging of the uterine cervix to assess collagen and water content changes in murine pregnancy.Biomedical optics express · 2019Article
Corrections and comments
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Authors and funding
32 authors.
Funding
Abstract
Premature cervical remodeling is a critical precursor of spontaneous preterm birth, and the remodeling process is characterized by an increase in tissue hydration. Nevertheless, current clinical measurements of cervical remodeling are subjective and detect only late events, such as cervical effacement and dilation. Here, we present a photoacoustic endoscope that can quantify tissue hydration by measuring near-infrared cervical spectra. We quantify the water contents of tissue-mimicking hydrogel phantoms as an analog of cervical connective tissue. Applying this method to pregnant women in vivo, we observed an increase in the water content of the cervix throughout pregnancy. The application of this technique in maternal healthcare may advance our understanding of cervical remodeling and provide a sensitive method for predicting preterm birth.
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Registered trials
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