Evidence map›Paper›PMID 30520039›Full record

ArticleThe Journal of comparative neurology2019

Long-range projections from sparse populations of GABAergic neurons in murine subplate.

Jacqueline Boon, Emma Clarke, Nicoletta Kessaris, André Goffinet, Zoltán Molnár, Anna Hoerder-Suabedissen

Open access · hybridAbstract read
In one paragraph

Article in The Journal of comparative neurology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Structure and function of neocortical layer 6b.Frontiers in cellular neuroscience · 2023
    Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Frontiers in neuroanatomy · 2019
    Article
  19. A Student's Guide to Neural Circuit Tracing.Frontiers in neuroscience · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 3 countries.

Jacqueline BoonDepartment of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom.
Emma ClarkeDepartment of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom.
Nicoletta KessarisWolfson Institute for Biomedical Research and Department of Cell and Developmental Biology, University College London, London, United Kingdom.
André GoffinetInstitute of Neuroscience, Université Catholique de Louvain, Louvain-la-Neuve, Belgium.
Zoltán MolnárDepartment of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom.ORCID 0000-0002-6852-6004
Anna Hoerder-SuabedissenDepartment of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom.ORCID 0000-0003-1953-7871
University of Oxford · GBRoyal Free London NHS Foundation Trust · GBUCLouvain · BEUniversity of Calgary · CAWolfson Foundation · GB

Funding

Biotechnology and Biological Sciences Research Council BB/F003285/1Biotechnology and Biological Sciences Research Council BB/N009061/1Medical Research Council G0300200Medical Research Council G0700377Medical Research Council G0900901Medical Research Council MR/N026039/1Wellcome Trust 108726/Z/15/Z
6 · The paper itself

Abstract

The murine subplate contains some of the earliest generated populations of neurons in the cerebral cortex, which play an important role in the maturation of cortical inhibition. Here we present multiple lines of evidence, that the subplate itself is only very sparsely populated with GABAergic neurons at postnatal day (P)8. We used three different transgenic mouse lines, each of which labels a subset of GABAergic, ganglionic eminence derived neurons. Dlx5/6-eGFP labels the most neurons in cortex (on average 11% of NEUN+ cells across all layers at P8) whereas CGE-derived Lhx6-Cre::Dlx1-Venus

Indexed as

AnimalsCerebral CortexGABAergic NeuronsMiceMice, Transgenicconnective tissue growth factorGABAergic neuronRRID: AB_10000240RRID: AB_10000340RRID: AB_2298772RRID: AB_2619710RRID: AB_477652RRID: AB_638805subplate

Identifiers

PMID30520039
PMCPMC6492162
OpenAlexW2905212724

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.