Evidence map›Paper›PMID 30519867›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2019

Joint EANM/EANO/RANO practice guidelines/SNMMI procedure standards for imaging of gliomas using PET with radiolabelled amino acids and [

Ian Law, Nathalie L Albert, Javier Arbizu, Ronald Boellaard, Alexander Drzezga, Norbert Galldiks, Christian la Fougère, Karl-Josef Langen, Egesta Lopci, Val Lowe and 6 more

3 registry-linked trialsAbstract read
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 313 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
313citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05553041 early_phase1recruitingnot on this mapstarted 2024, after this paper: background citation

Evaluation of 18F-Fluciclovine PET-MRI to Differentiate Tumor Progression From Post-treatment Changes in Pediatric High-grade Glioma (HGG)

TypeinterventionalSponsorChildren's Hospital of PhiladelphiaRan2024 to 2027Enrolled30ConditionsGlioma, High Grade Glioma, Glioma, Malignant, Glioma IntracranialArms18F-Fluciclovine PET-MRI
NCT07481721 phase1not yet recruitingnot on this mapstarted 2026, after this paper: background citation

A Multicenter, Open-Label, Non-Randomized, Single-Arm Investigator-Initiated Trial to Evaluate the Safety and Efficacy of IL13Rα2 CAR-T Cells Secreting Anti-PD-L1 Antibody in Patients With Recurrent Malignant Glioma

TypeinterventionalSponsorMing YangRan2026 to 2027Enrolled24ConditionsRecurrent Malignant GliomaArmsIL13Rα2 CAR-T Cells Secreting Anti-PD-L1 Antibody
NCT07567196 recruitingnot on this mapstarted 2022, after this paper: background citation

ResPGlioma: Impact of PET-Guided Resection on Survival in High-Grade Gliomas - A Multicenter Prospective Study

TypeobservationalSponsorUniversita degli Studi di GenovaRan2022 to 2029Enrolled100ConditionsGlioma Glioblastoma Multiforme, Glioma, High Grade, Glioma Surgery, Positron-Emission Tomography(PET)
3 · Its place in the literature

Who cites it

313 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Guideline
  2. Guideline
  3. EANM practice guidelines for an appropriate use of PET and SPECT for patients with epilepsy.European journal of nuclear medicine and molecular imaging · 2024
    Guideline
  4. Pooled it
  5. DEGRO practical guideline for central nervous system radiation necrosis part 1: classification and a multistep approach for diagnosis.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2022
    Guideline
  6. Prospective Multicenter Evaluation of [Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
    Trial
  7. Annals of nuclear medicine · 2025
    Trial
  8. [Journal of neuro-oncology · 2026
    Article
  9. Article
  10. Review
  11. Review
  12. Review
  13. Review
  14. Article
  15. Molecular Brain Tumor Imaging Beyond [AJR. American journal of roentgenology · 2026
    Review
  16. Tumefactive demyelinating disorders as neoplasm mimics: description of a typical case and literature review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Review
  17. Article
  18. Review
  19. Review
  20. Review

253 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors.

Ian LawDepartment of Clinical Physiology, Nuclear Medicine and PET, Rigshospitalet, University of Copenhagen, 9, Blegdamsvej, 2100-DK, Copenhagen Ø, Denmark. ilaw@dadlnet.dk.ORCID http://orcid.org/0000-0001-9644-7496
Nathalie L AlbertDepartment of Nuclear Medicine, Ludwig-Maximilians-University, Munich, Germany.
Javier ArbizuDepartment of Nuclear Medicine, Clínica Universidad de Navarra, University of Navarre, Pamplona, Spain.
Ronald BoellaardDepartment of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, Groningen, The Netherlands.
Alexander DrzezgaDepartment of Nuclear Medicine, University Hospital Cologne, Cologne, Germany.
Norbert GalldiksDepartment of Neurology, University Hospital Cologne, Cologne, Germany.
Christian la FougèreDivision of Nuclear Medicine and Clinical Molecular Imaging, Department of Radiology, University of Tübingen, Tübingen, Germany.
Karl-Josef LangenInstitute of Neuroscience and Medicine (INM-3, -4), Forschungszentrum Julich, Julich, Germany.
Egesta LopciDepartment of Nuclear Medicine, Humanitas Clinical and Research Hospital, Rozzano, Italy.
Val LoweDepartment of Radiology, Nuclear Medicine, Mayo Clinic, Rochester, MN, USA.
Jonathan McConathyDivision of Molecular Imaging and Therapeutics, University of Alabama at Birmingham, Birmingham, AL, USA.
Harald H QuickHigh-Field and Hybrid MR Imaging, University Hospital Essen, Essen, Germany.
Bernhard SattlerDepartment for Nuclear Medicine, University Hospital Leipzig, Leipzig, Germany.
David M SchusterDivision of Nuclear Medicine and Molecular Imaging, Department of Radiology and Imaging Sciences, Emory University, Atlanta, GA, USA.
Jörg-Christian TonnDepartment of Neurosurgery, Ludwig-Maximilians-University Munich, Munich, Germany.
Michael WellerDepartment of Neurology, University Hospital Zurich, Zurich, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

These joint practice guidelines, or procedure standards, were developed collaboratively by the European Association of Nuclear Medicine (EANM), the Society of Nuclear Medicine and Molecular Imaging (SNMMI), the European Association of Neurooncology (EANO), and the working group for Response Assessment in Neurooncology with PET (PET-RANO). Brain PET imaging is being increasingly used to supplement MRI in the clinical management of glioma. The aim of these standards/guidelines is to assist nuclear medicine practitioners in recommending, performing, interpreting and reporting the results of brain PET imaging in patients with glioma to achieve a high-quality imaging standard for PET using FDG and the radiolabelled amino acids MET, FET and FDOPA. This will help promote the appropriate use of PET imaging and contribute to evidence-based medicine that may improve the diagnostic impact of this technique in neurooncological practice. The present document replaces a former version of the guidelines published in 2006 (Vander Borght et al. Eur J Nucl Med Mol Imaging. 33:1374-80, 2006), and supplements a recent evidence-based recommendation by the PET-RANO working group and EANO on the clinical use of PET imaging in patients with glioma (Albert et al. Neuro Oncol. 18:1199-208, 2016). The information provided should be taken in the context of local conditions and regulations.

Indexed as

Amino AcidsFluorodeoxyglucose F18Nuclear MedicinePractice Guidelines as TopicSocieties, MedicalAdultChildGliomaHumansImage Processing, Computer-AssistedIsotope LabelingPositron-Emission TomographyQuality ControlRecurrenceReference StandardsResearch DesignAmino AcidsFluorodeoxyglucose F18FDGFDOPAFETGliomaMETPET

Identifiers

PMID30519867
PMCPMC6351513

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.