Evidence map›Paper›PMID 30519849›Full record

ArticleDigestive diseases and sciences2019

Presumed Consent: A Potential Tool for Countries Experiencing an Organ Donation Crisis.

Sammy Saab, Satvir S Saggi, Mizna Akbar, Gina Choi

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Article in Digestive diseases and sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Observational
  10. Article
  11. Assessing Global Organ Donation Policies: Opt-In vs Opt-Out.Risk management and healthcare policy · 2021
    Review
  12. Article
  13. Observational
  14. Impact of donor lung quality on post-transplant recipient outcome in the Lung Allocation Score era in Eurotransplant - a historical prospective study.Transplant international : official journal of the European Society for Organ Transplantation · 2020
    Article
  15. Article
  16. How the "Opt-In" Option Optimizes Organ Donation Rates.Digestive diseases and sciences · 2019
    Article
  17. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Sammy SaabDepartment of Medicine, University of California at Los Angeles, Los Angeles, CA, USA. SSaab@mednet.ucla.edu.
Satvir S SaggiDepartment of Surgery, University of California at Los Angeles, Los Angeles, CA, USA.
Mizna AkbarDepartment of Surgery, University of California at Los Angeles, Los Angeles, CA, USA.
Gina ChoiDepartment of Medicine, University of California at Los Angeles, Los Angeles, CA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is currently an inadequate supply of allografts to meet the number of transplant candidates worldwide. A number of controversial policies, including implementation of a presumed consent organ donation system, have been considered to rectify the organ donation crisis.

aimsA secondary retrospective data analysis aimed to assess the impact of switching to a presumed consent organ donation model on organ donation rates.

methodsDeceased organ donation rates were compared before and after countries adopted presumed consent.

resultsSix countries met entry criteria. All six countries had an increase in liver donation rates, while 4 out of the six countries had an increase in kidney donation rates. The overall mean (± SD) liver donation rate was 3.23 (± 0.97) per million population (pmp) before the transition and 6.46 (± 1.81) pmp after the transition (p < 0.0001). The overall mean (± SD) kidney donation rate was 17.94 (± 3.34) pmp before the transition and 26.58 (± 4.23) pmp after the transition (p < 0.0001). The percentage increase in liver and kidney donation rates varied among countries, ranging from 28 to 1186%.

conclusionThe transition from explicit to presumed consent was associated with a significant increase in liver donation rates in all countries that met our criteria, while the effect on kidney donation rates was partially realized. Although presumed consent alone is unlikely to explain the increase in donation rates, the adoption of such a policy may prove to be a worthwhile risk for countries experiencing consistently low organ donation rates.

Indexed as

InternationalityPresumed ConsentHumansOrgan TransplantationRegistriesRetrospective StudiesTissue and Organ ProcurementTissue DonorsKidney transplantationLiver transplantationOrgan procurementPresumed consentWaiting lists

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.