Evidence map›Paper›PMID 30519808›Full record

ArticleHeart and vessels2019

Diastolic wall strain as a predictor of age-related cardiovascular events in patients with preserved left ventricular ejection fraction.

Satoshi Tsujimoto, Yoko Miyasaka, Yoshinobu Suwa, Naoki Taniguchi, Shoko Kittaka, Kazuhiro Yamamoto, Ichiro Shiojima

Abstract read
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In one paragraph

Article in Heart and vessels, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Satoshi TsujimotoDivision of Cardiology, Department of Medicine II, Kansai Medical University, 2-5-1, Shin-machi, Hirakata, 573-1010, Osaka, Japan.
Yoko MiyasakaDivision of Cardiology, Department of Medicine II, Kansai Medical University, 2-5-1, Shin-machi, Hirakata, 573-1010, Osaka, Japan. miyasaka@hirakata.kmu.ac.jp.
Yoshinobu SuwaDivision of Cardiology, Department of Medicine II, Kansai Medical University, 2-5-1, Shin-machi, Hirakata, 573-1010, Osaka, Japan.
Naoki TaniguchiDivision of Cardiology, Department of Medicine II, Kansai Medical University, 2-5-1, Shin-machi, Hirakata, 573-1010, Osaka, Japan.
Shoko KittakaDivision of Cardiology, Department of Medicine II, Kansai Medical University, 2-5-1, Shin-machi, Hirakata, 573-1010, Osaka, Japan.
Kazuhiro YamamotoDepartment of Molecular Medicine and Therapeutics, Faculty of Medicine, Tottori University, Tottori, Japan.
Ichiro ShiojimaDivision of Cardiology, Department of Medicine II, Kansai Medical University, 2-5-1, Shin-machi, Hirakata, 573-1010, Osaka, Japan.

Funding

Grant-in-Aid for Scientific Research (C) 26461096
6 · The paper itself

Abstract

Diastolic wall strain (DWS) was reported as a simple and feasible echocardiographic index in assessing left ventricular (LV) diastolic stiffness. We sought to evaluate whether DWS predicts age-related cardiovascular events. Patients referred for transthoracic echocardiogram, those with preserved LV ejection fraction and no clinical heart failure were studied. Cardiovascular events were ascertained using Framingham criteria (myocardial infarction, coronary insufficiency, stroke, transient ischemic attack, congestive heart failure, or cardiovascular death). DWS was calculated with a validated formula. Cox proportional hazards modeling was used to assess the risk of cardiovascular events. Of a total number of 962 patients (mean age 60.9 ± 14.9 years, 48.0% men), 69 (7.2%) developed at least 1 cardiovascular event during a mean follow-up of 43 ± 32 months. After adjusting for cardiovascular comorbidities in a multivariable model, low DWS (≦ 0.33) was a significant independent predictor of cardiovascular events [hazard ratio (HR): 1.87, 95% confidential interval (CI) 1.04-3.36, P = 0.04]. Echocardiographic assessment of DWS may help in identifying the patients at increased risk for future age-related cardiovascular events.

Indexed as

EchocardiographyVentricular Function, LeftAgedCardiovascular DiseasesDiastoleFemaleHumansMaleMiddle AgedPrognosisProportional Hazards ModelsCardiovascular eventsEchocardiographyRisk factors

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.