Trial reportPrevention science : the official journal of the Society for Prevention Research2019
Testing the keepin' it REAL Substance Use Prevention Curriculum Among Early Adolescents in Guatemala City.
Trial report in Prevention science : the official journal of the Society for Prevention Research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Primary-level and community worker interventions for the prevention of mental disorders and the promotion of well-being in low- and middle-income countries.The Cochrane database of systematic reviews · 2023Pooled it
- Drug Use Prevention in Low-income Neighborhoods of Montevideo-Uruguay: the Effectiveness of Mantente REAL in Public Elementary Schools.Journal of prevention (2022) · 2026Trial
- Efficacy of the Mexican version of the keepin' it REAL school-based prevention program in addressing multi-substance use from early to mid-adolescence.Drug and alcohol dependence · 2025Trial
- Keepin' It REAL-Mantente REAL in Mexico: a Cluster Randomized Controlled Trial of a Culturally Adapted Substance Use Prevention Curriculum for Early Adolescents.Prevention science : the official journal of the Society for Prevention Research · 2021Trial
- Testing a Culturally Adapted Youth Substance Use Prevention Program in a Mexican Border City:Substance use & misuse · 2021Trial
- Effectiveness of School-Based Integrated Mental Health and Substance Use Prevention Programs for Adolescents: A Systematic Review and Meta-Analysis.Behavioral sciences (Basel, Switzerland) · 2026Review
- Feasibility, Acceptability, and Utility of the Keepin' It REAL Program for Preventing Adolescent Substance Use in Nigeria.Journal of prevention (2022) · 2026Article
- The power of the social: A systematic review and meta-analysis of social interventions in Global Mental Health.PLOS mental health · 2026Article
- Addressing the needs for cultural adaptation of DARE-keepin' it REAL among Brazilian students: strategies to improve implementation.Substance abuse treatment, prevention, and policy · 2024Article
- Mental health and well-being for the prevention of substance use disorders.Indian journal of psychiatry · 2024Article
- Types of Offers of Combustible Cigarettes, E-Cigarettes, and Betel Nut Experienced by Guam Youths.International journal of environmental research and public health · 2023Article
- Social Validity in Spain of the Mantente REAL Prevention Program for Early Adolescents : Social Validity of Mantente Real in Spain.Journal of prevention (2022) · 2023Article
- Community perceptions of vaccine advocacy for children under five in rural Guatemala.PLOS global public health · 2023Article
- Guam Adolescents' Use of Strategies to Resist Cigarette, e-Cigarette, and Betel Nut Offers: Findings from a Focus Group Study.Substance use & misuse · 2023Article
- Implementation fidelity of a Brazilian drug use prevention program and its effect among adolescents: a mixed-methods study.Substance abuse treatment, prevention, and policy · 2022Article
- Applying a Pattern-Centered Approach to Assess the Effect of a School-Based Drug Use Prevention Program in Brazil: A Cluster Randomized Controlled Trial.Journal of prevention (2022) · 2022Article
- Belief patterns and drug use in a sample of Brazilian youth: an exploratory latent class analysis.Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) · 2020Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
This article describes a test in Guatemala City of Mantente REAL, a linguistically adapted version of the keepin' it REAL universal substance use prevention curriculum for early adolescents that teaches culturally grounded drug resistance, risk assessment, and decision making skills. Academic researchers collaborated with a local non-profit to recruit and randomize 12 elementary schools in Guatemala City to intervention and comparison conditions. Regular classroom teachers were trained to deliver the ten-lesson Mantente REAL (MR) manualized curriculum to sixth-grade students. Parents provided passive consent and students gave active assent for data collection, which occurred between February 2013 and September 2014. Two academic year cohorts of students participated (n = 676; 53% male; M age = 12.2). All students completed a pretest questionnaire before the curriculum lessons began in intervention schools and a posttest (87% matched) 4 months later, 1 month after the final lesson. We assessed the MR intervention with paired t tests, effect sizes (Cohen's d), and general linear models adjusted for baseline, attrition, non-linear distributions, and school-level clustering. Results indicated that MR can be an effective school-based prevention approach in Guatemala. The MR participants reported pretest-to-posttest changes in desirable directions on substance use behaviors, attitudinal antecedents of substance use, and acquisition of drug resistance skills. The comparison group generally changed in undesirable directions. In linear models, the MR participants, relative to the comparison group, reported less cigarette and marijuana use, less positive drug use expectancies, and greater use of drug resistance skills. Intervention effect sizes were between .2 and .3.
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