Evidence map›Paper›PMID 30519675›Full record

ArticleLife science alliance2018

Peroxisome biogenesis deficiency attenuates the BDNF-TrkB pathway-mediated development of the cerebellum.

Yuichi Abe, Masanori Honsho, Ryota Itoh, Ryoko Kawaguchi, Masashi Fujitani, Kazushirou Fujiwara, Masaaki Hirokane, Takashi Matsuzaki, Keiko Nakayama, Ryohei Ohgi and 4 more

Open access · goldAbstract read
In one paragraph

Article in Life science alliance, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Mammalian Homologue NME3 of DYNAMO1 Regulates Peroxisome Division.International journal of molecular sciences · 2020
    Article
  8. Article
  9. Article
  10. Peroxisome Deficiency Impairs BDNF Signaling and Memory.Frontiers in cell and developmental biology · 2020
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Yuichi AbeDivision of Organelle Homeostasis, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.
Masanori HonshoDivision of Organelle Homeostasis, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.
Ryota ItohGraduate School of Systems Life Sciences and Department of Biology, Faculty of Sciences, Kyushu University Graduate School, Fukuoka, Japan.
Ryoko KawaguchiGraduate School of Systems Life Sciences and Department of Biology, Faculty of Sciences, Kyushu University Graduate School, Fukuoka, Japan.
Masashi FujitaniDepartment of Molecular Neuroscience, Graduate School of Medicine, Osaka University, Osaka, Japan.
Kazushirou FujiwaraGraduate School of Systems Life Sciences and Department of Biology, Faculty of Sciences, Kyushu University Graduate School, Fukuoka, Japan.
Masaaki HirokaneGraduate School of Systems Life Sciences and Department of Biology, Faculty of Sciences, Kyushu University Graduate School, Fukuoka, Japan.
Takashi MatsuzakiGraduate School of Systems Life Sciences and Department of Biology, Faculty of Sciences, Kyushu University Graduate School, Fukuoka, Japan.
Keiko NakayamaDepartment of Molecular and Cellular Biology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.
Ryohei OhgiGraduate School of Systems Life Sciences and Department of Biology, Faculty of Sciences, Kyushu University Graduate School, Fukuoka, Japan.
Toshihiro MarutaniGraduate School of Systems Life Sciences and Department of Biology, Faculty of Sciences, Kyushu University Graduate School, Fukuoka, Japan.
Keiichi I NakayamaDepartment of Molecular and Cellular Biology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.
Toshihide YamashitaDepartment of Molecular Neuroscience, Graduate School of Medicine, Osaka University, Osaka, Japan.
Yukio FujikiDivision of Organelle Homeostasis, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.ORCID https://orcid.org/0000-0002-8138-6376
Kyushu University · JPJapan Science and Technology Agency · JPThe University of Osaka · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peroxisome biogenesis disorders (PBDs) manifest as neurological deficits in the central nervous system, including neuronal migration defects and abnormal cerebellum development. However, the mechanisms underlying pathogenesis remain enigmatic. Here, to investigate how peroxisome deficiency causes neurological defects of PBDs, we established a new PBD model mouse defective in peroxisome assembly factor Pex14p, termed

Identifiers

PMID30519675
PMCPMC6277683
OpenAlexW2903233699

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.