Evidence map›Paper›PMID 30519488›Full record

ArticleInternational journal of hypertension2018

Renal Dysfunction among Ghanaians Living with Clinically Diagnosed Hypertension in the Asutifi-South District: A Cross-Sectional Descriptive Study at the St. Elizabeth Hospital, Hwidiem.

Sylvester Yao Lokpo, James Osei-Yeboah, William K B A Owiredu, Francis Abeku Ussher, Verner Ndudiri Orish, Felix Gadzeto, Paul Ntiamoah, Felix Botchway, Ivan Muanah, Romeo Asumbasiya Aduko

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of hypertension, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Prevalence and Associated Risk Factors of Chronic Kidney Disease in an Elderly Population from Eastern China.International journal of environmental research and public health · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Sylvester Yao LokpoDepartment of Medical Laboratory Sciences, School of Allied Health Sciences, University of Health and Allied Sciences, Ho, Ghana.ORCID 0000-0002-1628-0735
James Osei-YeboahDepartment of Medical Laboratory Sciences, School of Allied Health Sciences, University of Health and Allied Sciences, Ho, Ghana.ORCID 0000-0001-7982-5707
William K B A OwireduDepartment of Molecular Medicine, School of Medical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.ORCID 0000-0002-8920-1284
Francis Abeku UssherFaculty of Health and Allied Sciences, Koforidua Technical University, Koforidua, Eastern Region, Ghana.
Verner Ndudiri OrishDepartment of Microbiology and Immunology, School of Medicine, University of Health and Allied Sciences, Ho, Ghana.
Felix GadzetoLaboratory Department, St. Elizabeth Hospital, Catholic Health Services, Hwidiem, Brong Ahafo Region, Ghana.
Paul NtiamoahLaboratory Department, St. Elizabeth Hospital, Catholic Health Services, Hwidiem, Brong Ahafo Region, Ghana.
Felix BotchwayDepartment of Chemical Pathology, University of Ghana, Accra, Ghana.
Ivan MuanahSt. Elizabeth Hospital, Catholic Health Services, Hwidiem, Brong Ahafo Region, Ghana.
Romeo Asumbasiya AdukoDepartment of Medical Laboratory Sciences, School of Allied Health Sciences, University of Health and Allied Sciences, Ho, Ghana.ORCID 0000-0002-0214-2761
University of Health and Allied Sciences · GHKoforidua Technical University · GHKomfo Anokye Teaching Hospital · GHUniversity of Ghana · GH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study aimed at evaluating the burden of renal dysfunction among people living with hypertension in the Asutifi-South District of the Brong Ahafo Region, who were attending clinic at the St. Elizabeth Hospital in Hwidiem. METHODOLOGY: A hospital-based, cross-sectional study was conducted among two hundred (200) hypertensive clients aged between 27 and 88 years who reported for clinical management from January to March, 2018. Data on sociodemography, comorbid disease status, antihypertensive medication, and their duration was obtained using a semistructured questionnaire and patient folders. Blood pressure, weight, and creatinine were measured using standard methods. Kidney function was assessed using Cockcroft Gault (CG), Four-Variable Modification of Diet in Renal Disease (4v-MDRD) and the Chronic Kidney Disease-Epidemiology Collaboration (CKD-EPI) equations. The 2012 Kidney Disease Improvement Global Outcome (KDIGO) Criteria were used to categorize renal function among study participants.

resultsRenal impairment was observed among 25.00%, 9.50%, and 10.50% of study participants using CG, 4v-MDRD, and CKD-EPI equations, respectively. With the exception of CKD-EPI equation, females significantly recorded higher scores compared to their male counterparts (28.95% vs 12.5%, 11.84%, vs 2.08%) using CG and 4v-MDRD, respectively. Participants aged 50 years or more recorded the highest renal impairment.

conclusionRenal dysfunction is common among people living with hypertension in the Asutifi-South District of the Brong Ahafo Region. Femininity, older age, disease comorbidity with diabetes, Thiazide diuretic and AR Blocker usage, and increasing duration of medication accounted for higher kidney dysfunction. Regular screening and management are therefore recommended to avert progression to end-stage renal failure (ESRD).

Identifiers

PMID30519488
PMCPMC6241342
OpenAlexW2900289107

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.