ArticleEcology and evolution2018
Maternal age effects on fecundity and offspring egg-to-adult viability are not affected by mitochondrial haplotype.
Article in Ecology and evolution, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 9 citations in OpenAlex.
- Longitudinal lineage tracing reveals early clonal attrition during Drosophila midgut aging.PLoS biology · 2026Article
- Transcriptional memory of dFOXO activation in youth curtails later-life mortality through chromatin remodeling and Xbp1.Nature aging · 2022Article
- Parental breeding age effects on descendants' longevity interact over 2 generations in matrilines and patrilines.PLoS biology · 2019Article
- Inbreeding depression causes reduced fecundity in Golden Retrievers.Mammalian genome : official journal of the International Mammalian Genome Society · 2019Article
- Age of Both Parents Influences Reproduction and Egg Dumping Behavior in Drosophila melanogaster.The Journal of heredity · 2019Article
- Life History Effects Linked to an Advantage forInsects · 2019Article
- Maternal age effects on fecundity and offspring egg-to-adult viability are not affected by mitochondrial haplotype.Ecology and evolution · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
While numerous studies have demonstrated that mitochondrial genetic variation can shape organismal phenotype, the level of contribution the mitochondrial genotype makes to life-history phenotype across the life course remains unknown. Furthermore, a clear technical bias has emerged in studies of mitochondrial effects on reproduction, with many studies conducted on males, but few on females. Here, we apply a classic prediction of the evolutionary theory of aging to the mitochondrial genome, predicting the declining force of natural selection with age will have facilitated the accumulation of mtDNA mutations that confer late-life effects on female reproductive performance. This should lead to increased levels of mitochondrial genetic variation on reproduction at later-life stages. We tested this hypothesis using thirteen strains of
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.