Evidence map›Paper›PMID 30519326›Full record

ArticleJournal of Cancer2018

Predictors of Residual T1 High Grade on Re-Transurethral Resection in a Large Multi-Institutional Cohort of Patients with Primary T1 High-Grade/Grade 3 Bladder Cancer.

Matteo Ferro, Giuseppe Di Lorenzo, Carlo Buonerba, Giuseppe Lucarelli, Giorgio Ivan Russo, Francesco Cantiello, Abdal Rahman Abu Farhan, Savino Di Stasi, Gennaro Musi, Rodolfo Hurle and 25 more

Open access · goldAbstract read
In one paragraph

Article in Journal of Cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. Pooled it
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  7. CT-based deep learning radiomics nomogram for the prediction of pathological grade in bladder cancer: a multicenter study.Cancer imaging : the official publication of the International Cancer Imaging Society · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

35 authors at 14 institutions in 4 countries.

Matteo FerroDivision of Urology, European Institute of Oncology, Milan, Italy.
Giuseppe Di LorenzoDepartment of Clinical Medicine and Surgery, Federico II University of Naples, Naples, Italy.
Carlo BuonerbaDepartment of Clinical Medicine and Surgery, Federico II University of Naples, Naples, Italy.
Giuseppe LucarelliDepartment of Emergency and Organ Transplantation, Urology, Andrology and Kidney Transplantation Unit, University of Bari, Bari, Italy.
Giorgio Ivan RussoDepartment of Urology, University of Catania, Catania, Italy.
Francesco CantielloDepartment of Urology, Magna Graecia University of Catanzaro, Catanzaro, Italy.
Abdal Rahman Abu FarhanDepartment of Urology, Magna Graecia University of Catanzaro, Catanzaro, Italy.
Savino Di StasiUrology Unit, Policlinico Tor Vergata, University of Rome, Rome, Italy.
Gennaro MusiDivision of Urology, European Institute of Oncology, Milan, Italy.
Rodolfo HurleDepartment of Urology, Istituto Clinico Humanitas, Clinical and Research Hospital, Milan, Italy.
Serretta VincenzoDivision of Urology, University of Palermo, Palermo, Italy.
Gian Maria BusettoDepartment of Urology, La Sapienza University of Rome, Rome, Italy.
Ettore De BerardinisDepartment of Urology, La Sapienza University of Rome, Rome, Italy.
Sisto PerdonàDepartment of Uro-Gynaecological Oncology, Istituto Nazionale Tumori "Fondazione G. Pascale", IRCCS, Naples, Italy.
Marco BorghesiDepartment of Urology, University of Bologna, Bologna, Italy.
Riccardo SchiavinaDepartment of Urology, University of Bologna, Bologna, Italy.
Gilberto L AlmeidaDepartment of Urology, University of Vale do Itajaí, Itajaí, Brazil.
Pierluigi BoveDepartment of Experimental Medicine and Surgery, Urology Unit, Azienda Policlinico Tor Vergata, Rome, Italy.
Estevao LimaDepartment of CUF Urology and Life and Health Sciences Research Institute, School of Medicine, University of Minho, Portugal.
Giovanni GrimaldiDepartment of CUF Urology and Life and Health Sciences Research Institute, School of Medicine, University of Minho, Portugal.
Deliu Victor MateiDivision of Urology, European Institute of Oncology, Milan, Italy.
Francesco Alessandro MistrettaDivision of Urology, European Institute of Oncology, Milan, Italy.
Nicolae CrisanDepartment of Urology, University of Medicine and Pharmacy "Iuliu Hațieganu", Cluj-Napoca, Romania.
Daniela TerraccianoDepartment of Translational Medical Sciences, University of Naples "Federico II", Naples, Italy.
Verze PaoloDepartment of Neurosciences, Sciences of Reproduction and Odontostomatology, Urology Unit, University of Naples "Federico II", Naples, Italy.
Michele BattagliaDepartment of Clinical Medicine and Surgery, Federico II University of Naples, Naples, Italy.
Giorgio GuazzoniDepartment of Urology, Istituto Clinico Humanitas, Clinical and Research Hospital, Milan, Italy.
Riccardo AutorinoDivision of Urology, Virginia Commonwealth University, Richmond, VA, USA.
Giuseppe MorgiaIstituto Zooprofilattico Sperimentale del Mezzogiorno, Portici, Italy.
Rocco DamianoDepartment of Emergency and Organ Transplantation, Urology, Andrology and Kidney Transplantation Unit, University of Bari, Bari, Italy.
Matteo MutoDepartment of Clinical Medicine and Surgery, Federico II University Medical School of Naples, Italy.
Roberto La RoccaDepartment of Neurosciences, Sciences of Reproduction and Odontostomatology, Urology Unit, University of Naples "Federico II", Naples, Italy.
Vincenzo MironeDepartment of Neurosciences, Sciences of Reproduction and Odontostomatology, Urology Unit, University of Naples "Federico II", Naples, Italy.
Ottavio de CobelliDivision of Urology, European Institute of Oncology, Milan, Italy.
Mihai Dorin VartolomeiDivision of Urology, European Institute of Oncology, Milan, Italy.
University of Naples Federico II · ITEuropean Institute of Oncology · ITIstituto Zooprofilattico Sperimentale del Mezzogiorno · ITMagna Graecia University · ITPoliclinico Tor Vergata · ITSapienza University of Rome · ITUniversity of Bari Aldo Moro · ITUniversity of Bologna · ITFederico II University Hospital · ITUniversidade do Vale do Itajaí · BRUniversitatea de Medicină, Farmacie, Științe și Tehnologie „George Emil Palade” din Târgu Mureș · ROUniversity of Catania · ITUniversity of Palermo · ITVirginia Commonwealth University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this multi-institutional study was to identify predictors of residual high-grade (HG) disease at re-transurethral resection (reTUR) in a large cohort of primary T1 HG/Grade 3 (G3) bladder cancer patients. A total of 1155 patients with primary T1 HG/G3 bladder cancer from 13 academic institutions that underwent a reTUR within 6 weeks after first TUR were evaluated. Logistic regression analysis was performed to assess the association of predictive factors with residual HG at reTUR. Residual HG cancer was found in 288 (24.9%) of patients at reTUR. Patients presenting residual HG cancer were more likely to have carcinoma in situ (CIS) at first resection (p<0.001), multiple tumors (p=0.02), and tumor size larger than 3 cm (p=0.02). Residual HG disease at reTUR was associated with increased preoperative neutrophil-to-lymphocytes ratio (NLR) (p=0.006) and body mass index (BMI)>=25 kg/m

Indexed as

bladder cancerhigh-gradeneutrophil-to-lymphocytes ratiore-transurethral resection

Identifiers

PMID30519326
PMCPMC6277616
OpenAlexW2898593457

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.