Evidence map›Paper›PMID 30519236›Full record

ArticleFrontiers in immunology2018

Epstein-Barr Virus-Associated T-Cell Lymphoproliferative Disorder Presenting as Chronic Diarrhea and Intestinal Bleeding: A Case Report.

Yaxin Wang, Yajun Li, Xiangwei Meng, Xiumei Duan, Meilan Wang, Wenqing Chen, Tongyu Tang, Yuqin Li

Open access · goldAbstract readCase Reports
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 18 citations in OpenAlex.

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  10. Epstein-Barr virus seroprevalence and viral load at disease onset in children with inflammatory bowel disease.JGH open : an open access journal of gastroenterology and hepatology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Yaxin WangDepartment of Gastroenterology, Ordos Central Hospital, Dongsheng, China.
Yajun LiDepartment of Gastroenterology, Bethune First Affiliated Hospital of Jilin University, Changchun, China.
Xiangwei MengDepartment of Gastroenterology, Bethune First Affiliated Hospital of Jilin University, Changchun, China.
Xiumei DuanDepartment of Pathology, Bethune First Affiliated Hospital of Jilin University, Changchun, China.
Meilan WangDepartment of Gastroenterology, The Hospital of Jilin Province, Changchun, China.
Wenqing ChenDepartment of Gastroenterology, Bethune First Affiliated Hospital of Jilin University, Changchun, China.
Tongyu TangDepartment of Gastroenterology, Bethune First Affiliated Hospital of Jilin University, Changchun, China.
Yuqin LiDepartment of Gastroenterology, Bethune First Affiliated Hospital of Jilin University, Changchun, China.
First Bethune Hospital of Jilin University · CNXian Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Systemic Epstein-Barr virus-positive T-cell lymphoproliferative childhood disease (EBV+ T-LPD) is extremely rare. Primary acute or chronic active Epstein-Barr virus infection triggers EBV+ T-LPD's onset and the disease involves clonal proliferation of infected T-cells with activated cytotoxic phenotype. The adult-onset EBV+ T-LPD (ASEBV+ T-LPD) is even rarer and needs to be extensively studied. Further, according to literature review, it is a challenge to find patients who are immunocompetent and diagnosed with ASEBV+ T-LPD involving gastrointestinal tract. This case report discusses a previously healthy middle aged woman who presented with unique symptoms mimicking inflammatory bowel disease, and required a total colectomy and terminal ileum rectomy, as reveled by endoscopic examinations, due to severe gastrointestinal bleeding. Post-surgery histopathological findings were confirmatory for the diagnosis of ASEBV+ T-LPD (II: Borderline). This patient died 7 months after the diagnosis.

Indexed as

Cell ProliferationChronic DiseaseColectomyCytotoxicity, ImmunologicDiagnosis, DifferentialDiarrheaEpstein-Barr Virus InfectionsFatal OutcomeFemaleHemorrhageHerpesvirus 4, HumanHumansInflammatory Bowel DiseasesIntestinesLymphocyte ActivationLymphoproliferative Disordersclinical featuresdifferential diagnosisendoscopic featuresEpstein-Barr virus infectionT-cell lymphoproliferative disease

Identifiers

PMID30519236
PMCPMC6251325
OpenAlexW2900938079

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.