ArticleClinical epidemiology2018
Colonoscopy-related complications in a nationwide immunochemical fecal occult blood test-based colorectal cancer screening program.
Article in Clinical epidemiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.
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Who cites it
16 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Deaths and cardiopulmonary events following colorectal cancer screening-A systematic review with meta-analyses.PloS one · 2024Pooled it
- Pooled it
- Pooled it
- Trial
- Adverse events after colonoscopy in a randomised colorectal cancer screening trial.BMJ open gastroenterology · 2024Trial
- Improvement Effect ofFrontiers in immunology · 2022Trial
- Colon capsule endoscopy in colorectal cancer screening: a randomised controlled trial.BMJ open gastroenterology · 2020Trial
- Short term complications of conisation and long term effects on fertility related outcomes in Denmark: register based nationwide cohort study.BMJ (Clinical research ed.) · 2025Article
- Physical harms in colorectal cancer screening: An overview of the reporting in systematic reviews and randomised controlled trials.PloS one · 2025Review
- The optimal use of colon capsule endoscopes in clinical practice.Therapeutic advances in chronic disease · 2022Review
- Colon capsule endoscopy in colorectal cancer screening: Interim analyses of randomized controlled trial CareForColon2015.Endoscopy international open · 2021Article
- Adverse events of colonoscopy in a colorectal cancer screening program with fecal immunochemical testing: a population-based observational study.Endoscopy international open · 2021Article
- The Addition of Other Fecal Biomarkers Does Not Improve the Diagnostic Accuracy of Immunochemical Fecal Occult Blood Test Alone in a Colorrectal Cancer Screening Cohort.Frontiers in medicine · 2021Article
- Triage May Improve Selection to Colonoscopy and Reduce the Number of Unnecessary Colonoscopies.Cancers · 2020Article
- The combination of quantitative faecal occult blood test and faecal calprotectin is a cost-effective strategy to avoid colonoscopies in symptomatic patients without relevant pathology.Therapeutic advances in gastroenterology · 2020Article
- Observational
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe Danish national screening program for colorectal cancer (CRC) consists of an immunochemical fecal occult blood test (iFOBT) followed by colonoscopy. The Danish Colorectal Cancer Screening Database (DCCSD) records data on the incidence of hospital-registered complications after colonoscopy. However, the validity of these data is unknown, and the incidence of complications is potentially underreported.
objectiveTo evaluate the validity of the colonoscopy complications registered in the DCCSD by using medical records as the reference. Further, to evaluate the incidence of complications leading to hospital contact.
methodsAmong 14,671 individuals with a positive iFOBT result and a colonoscopy procedure performed from March 3, 2014 to December 31, 2014, we selected 295 individuals for medical record review. We calculated sensitivity as the proportion of true complications registered in the DCCSD out of all complications found in the medical records, and the positive predictive value (PPV) as the number of true complications in the DCCSD out of all DCCSD-registered complications. On the basis of the medical record data, we calculated the incidence proportion of hospital-registered complications overall and by subtype.
resultsIn total, we reviewed 286 records and found 102 individuals with at least one complication. The sensitivity of the DCCSD for any complication was 29.4% (95% CI: 20.8-39.3) and the PPV was 88.2% (95% CI: 72.6-96.7). On the basis of the medical record data, the incidence proportion of any complication after colonoscopy was 0.70% (95% CI: 0.57-0.84) and that of perforation or lesion was 0.10% (95% CI: 0.06-0.17); bleeding, 0.41% (95% CI: 0.31-0.53); post-polypectomy syndrome, 0.16% (95% CI: 0.10-0.24); and other medical complications, 0.04 (95% CI: 0.02-0.09).
conclusionThe DCCSD has low sensitivity for complications, and improvements in data registration are warranted. The incidence proportion of any hospital-treated post-colonoscopy complication was 0.70% in 2014, which was the first year of the Danish national CRC screening program. This is within the range of complications reported by other studies.
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