Evidence map›Paper›PMID 30519103›Full record

ArticleCancer management and research2018

Impact of the anterior commissure involvement on the survival of early glottic cancer treated with cricohyoidoepiglottopexy: a retrospective study.

Eugenia Allegra, Vincenzo Saita, Alfio Azzolina, Massimo De Natale, Maria Rita Bianco, Domenico Michele Modica, Aldo Garozzo

Open access · goldAbstract read
In one paragraph

Article in Cancer management and research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

  1. Observational
  2. Comparison of oncological outcomes between transoral laser microsurgery and open partial laryngectomy in T2 glottic carcinoma with anterior commissure involvement.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  3. Article
  4. Trends in Treatment Choice for Early Glottic Cancer.Journal of clinical medicine · 2025
    Article
  5. Analysis of swallowing and voice-related quality of life in patients after supracricoid partial laryngectomy.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024
    Article
  6. Article
  7. Article
  8. Olfactory function in laryngectomised patients: tracheo-oesophagealActa otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2023
    Article
  9. Article
  10. Review
  11. Article
  12. Outcomes Following Transoral Laser Microsurgery for T1b and T2a Glottic Squamous Cell Carcinoma With and Without Anterior Commissure Involvement: A Retrospective Chart Review.Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Eugenia AllegraOtolaryngology, Department of Health Sciences, University of Catanzaro, Catanzaro, Italy, eualle@unicz.it.
Vincenzo SaitaOtolaryngology Unit, Cannizzaro Hospital, Catania, Italy.
Alfio AzzolinaOtolaryngology Unit, Cannizzaro Hospital, Catania, Italy.
Massimo De NataleOtolaryngology Unit, Cannizzaro Hospital, Catania, Italy.
Maria Rita BiancoOtolaryngology, Department of Health Sciences, University of Catanzaro, Catanzaro, Italy, eualle@unicz.it.
Domenico Michele ModicaOtolaryngology Unit, University of Palermo, Palermo, Italy.
Aldo GarozzoOtolaryngology, Department of Health Sciences, University of Catanzaro, Catanzaro, Italy, eualle@unicz.it.
Magna Graecia University · ITOspedale Cannizzaro · ITUniversity of Palermo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLaryngeal early glottic tumors can benefit from different treatment modalities, including transoral laser microsurgery, open partial horizontal laryngectomy (OPHL), and radiotherapy. However, the treatment of early glottic tumors with the involvement of the anterior commissure remains controversial. The studies about the role of anterior commissure involvement in oncologic outcomes in patients with early glottic cancer treated with supracricoid laryngectomy (SCL) are very few. For this reason, we conducted a retrospective study to evaluate local recurrence-free survival and specific survival in patients with and without involvement of the anterior commissure who underwent SCL with cricohyoidoepiglottopexy.

methodsThis retrospective study has been carried out on patients with T1b-T2 glottic squamous cell carcinoma submitted to SCL with cricohyoidoepiglottopexy. The patients' demographic and clinical data were collected, and the histological findings of the surgical specimens were reviewed to identify patients who had involvement of the anterior commissure.

resultsA total of 72 patients were included in the study; two of them were female and 70 were male. The mean age at diagnosis was 61.5±8.0 SD years. In 26 of the 72 (36.2%) patients, anterior commissure was not pathologically involved (group A), while in 46 (63.8%) patients, it was involved (group B). The 5-year local recurrence-free survival rate was 96.1% and 93.48% in groups A and B, respectively,

conclusionSCL with cricohyoidoepiglottopexy seems to be an adequate treatment modality, even for T1b-T2 glottic tumors with anterior commissure involvement.

Indexed as

cricohyoidoepiglottopexylaryngeal canceropen partial horizontal laryngectomysupracricoid laryngectomy

Identifiers

PMID30519103
PMCPMC6234988
OpenAlexW2900400350

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.