Evidence map›Paper›PMID 30519067›Full record

ArticleClinical, cosmetic and investigational dermatology2018

Detection of tick-borne infection in Morgellons disease patients by serological and molecular techniques.

Marianne J Middelveen, Iris Du Cruz, Melissa C Fesler, Raphael B Stricker, Jyotsna S Shah

Open access · goldAbstract read
In one paragraph

Article in Clinical, cosmetic and investigational dermatology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Morgellons disease: a narrative review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024
    Review
  2. Article
  3. Article
  4. Dermatological and Genital Manifestations of Lyme Disease Including Morgellons Disease.Clinical, cosmetic and investigational dermatology · 2021
    Article
  5. Article
  6. Lyme Disease: Diversity ofHealthcare (Basel, Switzerland) · 2020
    Article
  7. Classification and Staging of Morgellons Disease: Lessons from Syphilis.Clinical, cosmetic and investigational dermatology · 2020
    Article
  8. Article
  9. MixedHealthcare (Basel, Switzerland) · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Marianne J MiddelveenAtkins Veterinary Services, Calgary, AB, Canada.
Iris Du CruzIGeneX Laboratories, Palo Alto, CA, USA.
Melissa C FeslerUnion Square Medical Associates, San Francisco, CA, USA, rstricker@usmamed.com.
Raphael B StrickerUnion Square Medical Associates, San Francisco, CA, USA, rstricker@usmamed.com.
Jyotsna S ShahIGeneX Laboratories, Palo Alto, CA, USA.
Medical Research Associates · USCalgary Laboratory Services · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMorgellons disease (MD) is a skin condition associated with Lyme disease (LD) and tick-borne illness. Patients with this skin disorder experience ulcerative lesions that contain multicolored filamentous collagen and keratin inclusions. Infection with various species of PATIENTS AND

methodsSera from 30 patients with MD were tested for antibody reactivity to antigens from the

resultsSeroreactivity to Bb, RFB or both was detected in 63% of the cohort, while positive PCR testing for Bb, RFB or both was detected in 53% of the cohort. Overall, 90% of patients tested positive for exposure and/or infection with

conclusionThe study demonstrates an association between MD and positive tests for both Bb and RFB spirochetes. In conjunction with previous studies, our study provides corroborative evidence linking MD to

Indexed as

BartonellaBorrelia burgdorferiLyme diseaseMorgellons diseaserelapsing fever Borreliatick-borne disease

Identifiers

PMID30519067
PMCPMC6233863
OpenAlexW2900369070

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.