ArticleInternational journal of nanomedicine2018
Curcumin nanoemulsion as a novel chemical for the treatment of acute and chronic toxoplasmosis in mice.
Article in International journal of nanomedicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.
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Who cites it
40 citing papers in PubMed, 1 synthesis or guideline pooled it, 78 citations in OpenAlex.
- The Search for Drugs Derived from Natural Products forCurrent topics in medicinal chemistry · 2024Pooled it
- Imidazopyridine derivatives as promising anti-RSC advances · 2026Article
- Anti-Advanced biomedical research · 2026Article
- Co-delivery of spiramycin and curcumin nanoemulsions for treating acute (RH strain) and chronic (Tehran strain) toxoplasmosis in BALB/c mice.Parasitology research · 2025Article
- Exploring the role of chitosan and curcumin-loaded chitosan nanoparticles against chronic toxoplasma infection in experimental mice.Scientific reports · 2025Article
- Linalool as a potential agent against Toxoplasma gondii: an in vitro study.BMC research notes · 2025Article
- Therapeutic effects of curcumin nanoemulsion on cyclophosphamide-induced testicular toxicity in adult male mice.Clinical and experimental reproductive medicine · 2025Article
- Development and Optimization ofGels (Basel, Switzerland) · 2025Article
- Nanoformulations for Hydrazones; Synthesis, Characterization, Parasitology, and Histopathology Investigations.ACS omega · 2025Article
- Article
- Black seed oil nanoemulsion containing albendazole against protoscoleces ofIranian journal of basic medical sciences · 2025Article
- Preparation of a nanoemulsion containing active ingredients of cannabis extract and its application for glioblastoma: in vitro and in vivo studies.BMC pharmacology & toxicology · 2024Article
- In vitro and in vivo anti-parasitic activity of curcumin nanoemulsion on Leishmania major (MRHO/IR/75/ER).BMC complementary medicine and therapies · 2024Article
- Therapeutic effect of curcumin nanoemulsion on cystic echinococcosis in BALB/c mice: a computerized tomography (CT) scan and histopathologic study evaluation.BMC complementary medicine and therapies · 2024Article
- Olive oil nanoemulsion containing curcumin: antimicrobial agent against multidrug-resistant bacteria.Applied microbiology and biotechnology · 2024Article
- Zinc Oxide and Magnesium-Doped Zinc Oxide Nanoparticles Ameliorate Murine Chronic Toxoplasmosis.Pharmaceuticals (Basel, Switzerland) · 2024Article
- Formulation and evaluation of atovaquone-loaded macrophage-derived exosomes againstMicrobiology spectrum · 2024Article
- Toward a Platform for the Treatment of Burns: An Assessment of Nanoemulsions vs. Nanostructured Lipid Carriers Loaded with Curcumin.Biomedicines · 2023Article
- Synthesis, X-ray Structure, Hirshfeld, DFT Conformational, Cytotoxic, and Anti-Toxoplasma Studies of New Indole-Hydrazone Derivatives.International journal of molecular sciences · 2023Article
- Nanoemulsion of Spiramycin against Tachyzoites ofIranian journal of public health · 2023Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aim of this study was to prepare curcumin nanoemulsion (CR-NE) to solve the problems associated with poor water solubility and low bioavailability of CR and to test its efficiency in the treatment of acute and chronic toxoplasmosis in mouse models. MATERIALS AND
methodsCR-NE 1% was prepared using spontaneous emulsification by soybean as oil phase; a mixture of Tween 80 and Tween 85 as surfactant; ethanol as cosurfactant and distilled water. Particle size and zeta potential of NE were assessed using Nano-ZS90 dynamic light scattering. Stability testing of NE was assessed after storage for 2 months at room temperature. In vivo experiments were carried out using 50 BALB/c mice inoculated with virulent RH strain (type I) and 50 BALB/c mice inoculated with avirulent Tehran strain (type II) of
resultsThe mean particle size and zeta potential of CR-NE included 215.66±16.8 nm and -29.46±2.65 mV, respectively, and were stable in particle size after a three freeze-thaw cycle. In acute phase experiment, the survival time of mice infected with RH strain of
conclusionResults from the current study showed the potential of CR-S and CR-NE in treatment of acute and chronic toxoplasmosis in mouse models for the first time. However, CR-NE was more efficient than CR-S, and it seems that CR-NE has a potential formula for the treatment of acute and chronic toxoplasmosis, especially in those with latent bradyzoites in brain.
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