Evidence map›Paper›PMID 30518864›Full record

ArticleNature2019

Inner ear development in cyclostomes and evolution of the vertebrate semicircular canals.

Shinnosuke Higuchi, Fumiaki Sugahara, Juan Pascual-Anaya, Wataru Takagi, Yasuhiro Oisi, Shigeru Kuratani

Open access · greenAbstract readComparative Study
PubMed Publisher
In one paragraph

Article in Nature, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 65 citations in OpenAlex.

  1. Article
  2. Unveiling Otolith Mystery: Contemporary Testing Approaches and Their Clinical Significance.World journal of otorhinolaryngology - head and neck surgery · 2026
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  11. Article
  12. Evolution and development of extraocular motor neurons, nerves and muscles in vertebrates.Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft · 2024
    Review
  13. Review
  14. Evidence That Ultrafast Nonquantal Transmission Underlies Synchronized Vestibular Action Potential Generation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
  15. Article
  16. ThreeFrontiers in cell and developmental biology · 2023
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Shinnosuke HiguchiDepartment of Biology, Graduate School of Science, Kobe University, Kobe, Japan.
Fumiaki SugaharaDivision of Biology, Hyogo College of Medicine, Nishinomiya, Japan.
Juan Pascual-AnayaEvolutionary Morphology Laboratory, RIKEN Cluster for Pioneering Research (CPR), Kobe, Japan.
Wataru TakagiPhysiology Laboratory, Atmosphere Ocean Research Institute, The University of Tokyo, Kashiwa, Japan.
Yasuhiro OisiLaboratory for Haptic Perception and Cognitive Physiology, RIKEN Center for Brain Science, Wako, Japan.
Shigeru KurataniLaboratory for Evolutionary Morphology, RIKEN Center for Biosystems Dynamics Research (BDR), Kobe, Japan. shigeru.kuratani@riken.jp.
Pioneer (Japan) · JPHyogo Medical University · JPKobe University · JPRIKEN Center for Brain Science · JPThe University of Tokyo · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Jawed vertebrates have inner ears with three semicircular canals, the presence of which has been used as a key to understanding evolutionary relationships. Ostracoderms, the jawless stem gnathostomes, had only two canals and lacked the lateral canal

Indexed as

OrganogenesisPhylogenyAnimalsGene Expression Regulation, DevelopmentalHagfishesLampreysMiceSemicircular CanalsSharksVertebratesZebrafish

Identifiers

PMID30518864
OpenAlexW2902991553

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.