Evidence map›Paper›PMID 30518823›Full record

ArticleInternational journal of obesity (2005)2019

Association between brown adipose tissue and bone mineral density in humans.

Guillermo Sanchez-Delgado, Borja Martinez-Tellez, Yolanda Garcia-Rivero, Francisco M Acosta, Juan M A Alcantara, Francisco J Amaro-Gahete, Jose M Llamas-Elvira, Luis Gracia-Marco, Jonatan R Ruiz

Abstract read
PubMed Publisher
In one paragraph

Article in International journal of obesity (2005), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Guillermo Sanchez-DelgadoPROFITH "PROmoting FITness and Health through physical activity" research group, Department of Physical Education and Sport, Faculty of Sport Sciences, University of Granada, Ctra. de Alfacar s/n, C.P., 18071, Granada, Spain. gsanchezdelgado@ugr.es.ORCID http://orcid.org/0000-0003-4455-2483
Borja Martinez-TellezPROFITH "PROmoting FITness and Health through physical activity" research group, Department of Physical Education and Sport, Faculty of Sport Sciences, University of Granada, Ctra. de Alfacar s/n, C.P., 18071, Granada, Spain.ORCID http://orcid.org/0000-0001-8783-1859
Yolanda Garcia-RiveroNuclear Medicine Department, "Virgen de las Nieves" University Hospital, Granada, Spain.
Francisco M AcostaPROFITH "PROmoting FITness and Health through physical activity" research group, Department of Physical Education and Sport, Faculty of Sport Sciences, University of Granada, Ctra. de Alfacar s/n, C.P., 18071, Granada, Spain.
Juan M A AlcantaraPROFITH "PROmoting FITness and Health through physical activity" research group, Department of Physical Education and Sport, Faculty of Sport Sciences, University of Granada, Ctra. de Alfacar s/n, C.P., 18071, Granada, Spain.
Francisco J Amaro-GahetePROFITH "PROmoting FITness and Health through physical activity" research group, Department of Physical Education and Sport, Faculty of Sport Sciences, University of Granada, Ctra. de Alfacar s/n, C.P., 18071, Granada, Spain.ORCID http://orcid.org/0000-0002-7207-9016
Jose M Llamas-ElviraNuclear Medicine Department, "Virgen de las Nieves" University Hospital, Granada, Spain.
Luis Gracia-MarcoPROFITH "PROmoting FITness and Health through physical activity" research group, Department of Physical Education and Sport, Faculty of Sport Sciences, University of Granada, Ctra. de Alfacar s/n, C.P., 18071, Granada, Spain.
Jonatan R RuizPROFITH "PROmoting FITness and Health through physical activity" research group, Department of Physical Education and Sport, Faculty of Sport Sciences, University of Granada, Ctra. de Alfacar s/n, C.P., 18071, Granada, Spain.ORCID http://orcid.org/0000-0002-7548-7138

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBrown adipose tissue (BAT) seems to play a role in bone morphogenesis. A negative association has been reported between BAT and bone mineral density (BMD) in women, but not in men. A panel of experts has recently published a set of recommendations for BAT assessment, and thus, to re-address previously reported associations is needed. This study aimed to investigate the association between cold-induced BAT

methodsNinety-eight healthy adults (68 women; 22 ± 2.2 years old; 24.3 ± 4.5 kg/m

resultsWe found no association between BMD and cold-induced BAT volume, mean, and maximal activity (all P > 0.1) in neither young and healthy men nor women. These results remained unchanged when adjusting by height, by body composition, and by objectively assessed physical activity. Sensitivity analyses using the criteria to quantify cold-induced BAT-related parameters applied in previous studies did not change the results.

conclusionsIn summary, our study shows that there is no association between cold-induced BAT and BMD in young healthy adults. Moreover, our data support the notion that previously shown associations between BAT and BMD in healthy non-calorically restricted individuals, could be driven by methodological issues related to BAT assessment and/or sample size limitations.

Indexed as

Cold TemperatureAbsorptiometry, PhotonAdipose Tissue, BrownAdolescentAdultBody CompositionBone DensityExerciseFemaleFluorodeoxyglucose F18HumansMalePositron Emission Tomography Computed TomographySpineWhole Body ImagingYoung AdultFluorodeoxyglucose F18

Identifiers

PMID30518823

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.