Evidence map›Paper›PMID 30518795›Full record

ArticleJournal of exposure science & environmental epidemiology2019

Metabolomic assessment of exposure to near-highway ultrafine particles.

Douglas I Walker, Kevin J Lane, Ken Liu, Karan Uppal, Allison P Patton, John L Durant, Dean P Jones, Doug Brugge, Kurt D Pennell

Abstract read
In one paragraph

Article in Journal of exposure science & environmental epidemiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Lipid nanoparticle GM-CSF replacement for autoimmune pulmonary alveolar proteinosis.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Clinical and inflammatory features of traffic-related diesel exposure in children with asthma.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2024
    Article
  19. Observational
  20. Article

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Douglas I WalkerClinical Biomarkers Laboratory, Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, School of Medicine, Emory University, Atlanta, GA, USA.
Kevin J LaneDepartment of Environmental Health, Boston University School of Public Health, Boston, MA, USA.
Ken LiuClinical Biomarkers Laboratory, Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, School of Medicine, Emory University, Atlanta, GA, USA.
Karan UppalClinical Biomarkers Laboratory, Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, School of Medicine, Emory University, Atlanta, GA, USA.
Allison P PattonHealth Effects Institute, Boston, MA, USA.
John L DurantDepartment of Civil and Environmental Engineering, Tufts University, Medford, MA, USA.
Dean P JonesClinical Biomarkers Laboratory, Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, School of Medicine, Emory University, Atlanta, GA, USA.
Doug BruggeDepartment of Civil and Environmental Engineering, Tufts University, Medford, MA, USA.
Kurt D PennellDepartment of Civil and Environmental Engineering, Tufts University, Medford, MA, USA. kurt_pennell@brown.edu.

Funding

Pilot Project ProgramP30ES019776 · NIEHS · EMORY UNIVERSITY · PI William Michael Caudle · 2013 to 2026
$22.6M
Graduate Training in the Pharmacological StudiesT32GM008602 · NIGMS · EMORY UNIVERSITY · PI HALL, RANDY A. · 1996 to 2021
$5.1M
Community Assessment of Freeway Pollution and HealthR01ES015462 · NIEHS · TUFTS UNIVERSITY BOSTON · PI BRUGGE, DOUG · 2008 to 2012
$2.5M
Cytoplasmic-nuclear redox signaling: Disruption by dietary cadmium levelsR01ES023485 · NIEHS · EMORY UNIVERSITY · PI GO KANG, YOUNG-MI, JONES, DEAN PAUL · 2014 to 2018
$1.8M
Orbitrap Elite/H-ESI BundleS10OD018006 · OD · EMORY UNIVERSITY · PI JONES, DEAN PAUL · 2014 to 2014
$600k
Mitochondria Environmental Stress Signaling NetworksR21ES025632 · NIEHS · EMORY UNIVERSITY · PI GO KANG, YOUNG-MI, JONES, DEAN PAUL · 2015 to 2017
$576k
NIEHS NIH HHS P30 ES019776NIEHS NIH HHS R01 ES015462NIEHS NIH HHS R01 ES023485NIEHS NIH HHS R21 ES025632NIGMS NIH HHS T32 GM008602NIH HHS S10 OD018006
6 · The paper itself

Abstract

Exposure to traffic-related air pollutants has been associated with increased risk of adverse cardiopulmonary outcomes and mortality; however, the biochemical pathways linking exposure to disease are not known. To delineate biological response mechanisms associated with exposure to near-highway ultrafine particles (UFP), we used untargeted high-resolution metabolomics to profile plasma from 59 participants enrolled in the Community Assessment of Freeway Exposure and Health (CAFEH) study. Metabolic variations associated with UFP exposure were assessed using a cross-sectional study design based upon low (mean 16,000 particles/cm

Indexed as

Environmental ExposureMetabolomicsAir PollutantsBiomarkersCross-Sectional StudiesFemaleHumansMaleMiddle AgedParticulate MatterVehicle EmissionsAir PollutantsBiomarkersParticulate MatterVehicle EmissionsExposomeHigh-resolution metabolomicsMetabolome-wide association studyTraffic-related air pollution

Identifiers

PMID30518795
PMCPMC6551325

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.