Evidence map›Paper›PMID 30518698›Full record

ArticleJCI insight2018

Transcranial optical imaging reveals a pathway for optimizing the delivery of immunotherapeutics to the brain.

Benjamin A Plog, Humberto Mestre, Genaro E Olveda, Amanda M Sweeney, H Mark Kenney, Alexander Cove, Kosha Y Dholakia, Jeffrey Tithof, Thomas D Nevins, Iben Lundgaard and 3 more

Abstract readPublished Erratum
In one paragraph

Article in JCI insight, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Article
  3. The glymphatic system and glioblastoma.Brain : a journal of neurology · 2026
    Review
  4. Cerebral small vessel disease: The impact of glymphopathy and sleep disorders.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2025
    Review
  5. Review
  6. Article
  7. Development of perivascular astrocyte processes.Frontiers in neuroscience · 2025
    Review
  8. Review
  9. The glymphatic system in migraine and other headaches.The journal of headache and pain · 2024
    Review
  10. Review
  11. Article
  12. Review
  13. Fluid transport in the brain.Physiological reviews · 2022
    Review
  14. Review
  15. The Glymphatic System (En)during Inflammation.International journal of molecular sciences · 2021
    Review
  16. Brain cerebrospinal fluid flow.Physical review fluids · 2021
    Article
  17. Review
  18. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Benjamin A Plog
Humberto Mestre
Genaro E Olveda
Amanda M Sweeney
H Mark Kenney
Alexander Cove
Kosha Y Dholakia
Jeffrey Tithof
Thomas D Nevins
Iben Lundgaard
Ting Du
Douglas H Kelley
Maiken Nedergaard

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID30518698
PMCPMC6328017

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.